Central Role of Gimap5 in Maintaining Peripheral Tolerance and T Cell Homeostasis in the Gut
Inflammatory bowel disease (IBD) including Crohn’s disease and ulcerative colitis is often precipitated by an abnormal immune response to microbiota due to host genetic aberrancies. Recent studies highlight the importance of the host genome and microflora interactions in the pathogenesis of mucosal...
Saved in:
Main Authors: | Mehari Endale, H. Ibrahim Aksoylar, Kasper Hoebe |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2015-01-01
|
Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2015/436017 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Role of hepatocyte RIPK1 in maintaining liver homeostasis during metabolic challenges
by: Weigao Zhang, et al.
Published: (2025-01-01) -
Immune Tolerance Regulation Is Critical to Immune Homeostasis
by: Lei Han, et al.
Published: (2025-01-01) -
LGR4 is essential for maintaining β-cell homeostasis through suppression of RANK
by: Joanna Filipowska, et al.
Published: (2025-02-01) -
Tubular MYDGF Slows Progression of Chronic Kidney Disease by Maintaining Mitochondrial Homeostasis
by: Xiaohan Liu, et al.
Published: (2025-01-01) -
Expression of the Autoimmune Regulator Gene and Its Relevance to the Mechanisms of Central and Peripheral Tolerance
by: Roberto Perniola
Published: (2012-01-01)