Association analysis between a VNTR intron 8 polymorphism of the dopamine transporter gene (SLC6A3) and obsessive- compulsive disorder in a Brazilian sample Análise de associação entre um polimorfismo VNTR no intron 8 do gene do transportador de dopamina (SLC6A3) e transtorno obsessivo-compulsivo em uma amostra brasileira

Association analysis between a VNTR intron 8 polymorphism of the dopamine transporter gene (SLC6A3) and obsessive- compulsive disorder in a Brazilian sample Análise de associação entre um polimorfismo VNTR no intron 8 do gene do transportador de dopamina (SLC6A3) e transtorno obsessivo-compulsivo em uma amostra brasileira

Family, twin and segregation analysis have provided evidences that genetic factors are implicated in the susceptibility for obsessive-compulsive disorder (OCD). Several lines of research suggest that the dopaminergic system may be involved in the pathophysiology of OCD. Thus, the aim of the present...

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Bibliographic Details
Main Authors: Karen Miguita, Quirino Cordeiro, Jacqueline Siqueira-Roberto, Roseli Gedanke Shavitt, José Carlos Ramos Castillo, Ana Regina Castillo, Euripedes Constantino Miguel, Homero Vallada
Format: Article
Language:English
Published: Thieme Revinter Publicações 2007-12-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
dopamina
associação genética
DAT1
alelo
genótipo
dopamine
obsessive-compulsive disorder
genetic association
allele
genotype
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000600002
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