The necessity of validity diagnostics when drawing causal inferences from observational data: lessons from a multi-database evaluation of the risk of non-infectious uveitis among patients exposed to Remicade®

The necessity of validity diagnostics when drawing causal inferences from observational data: lessons from a multi-database evaluation of the risk of non-infectious uveitis among patients exposed to Remicade®

Abstract Background Autoimmune disorders have primary manifestations such as joint pain and bowel inflammation but can also have secondary manifestations such as non-infectious uveitis (NIU). A regulatory health authority raised concerns after receiving spontaneous reports for NIU following exposure...

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Bibliographic Details
Main Authors: James Weaver, Erica A. Voss, Guy Cafri, Kathleen Beyrau, Michelle Nashleanas, Robert Suruki
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Medical Research Methodology
Subjects:
Observational study
Causal inference
Autoimmune disorders
Biologic agents
Non-infectious uveitis
Online Access:https://doi.org/10.1186/s12874-024-02428-7
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