Development of viral infectious clones and their applications based on yeast and bacterial artificial chromosome platforms

Development of viral infectious clones and their applications based on yeast and bacterial artificial chromosome platforms

Abstract Infectious Clones represent a foundational technique in the field of reverse genetics, allowing for the construction and manipulation of full-length viral genomes. The main methods currently used for constructing viral infectious clones include Transformation-associated recombination (TAR),...

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Bibliographic Details
Main Authors: Yiyi Wu, Shangqing Gao, Guanya Liu, Mengwei Wang, Ruixiao Tan, Baoying Huang, Wenjie Tan
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Molecular Biomedicine
Subjects:
Virus Infectious Clones
Reverse genetics
Yeast artificial chromosome (YAC)
Bacterial artificial chromosome (BAC)
Application
Online Access:https://doi.org/10.1186/s43556-025-00266-7
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