Development of viral infectious clones and their applications based on yeast and bacterial artificial chromosome platforms

Abstract Infectious Clones represent a foundational technique in the field of reverse genetics, allowing for the construction and manipulation of full-length viral genomes. The main methods currently used for constructing viral infectious clones include Transformation-associated recombination (TAR),...

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Bibliographic Details
Main Authors: Yiyi Wu, Shangqing Gao, Guanya Liu, Mengwei Wang, Ruixiao Tan, Baoying Huang, Wenjie Tan
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Molecular Biomedicine
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Online Access:https://doi.org/10.1186/s43556-025-00266-7
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