Prevalence and risk factors of pulmonary infection in elderly patients with mental disorders： a Meta-analysis
BackgroundWith the exacerbation of population aging， the number of elderly patients with mental disorders has increased significantly. The high prevalence of pulmonary infection in the aging population has largely contributed to the increased medical burdens and mortality rate， so preventing pulmona...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of Sichuan Mental Health
2025-04-01
|
| Series: | Sichuan jingshen weisheng |
| Subjects: | |
| Online Access: | http://www.psychjm.net.cn/scjswszz/ch/reader/view_abstract.aspx?file_no=202502014&flag=1 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849712995790225408 |
|---|---|
| author | Wu Yuxiao Xing Haoran Bao Tianhao |
| author_facet | Wu Yuxiao Xing Haoran Bao Tianhao |
| author_sort | Wu Yuxiao |
| collection | DOAJ |
| description | BackgroundWith the exacerbation of population aging， the number of elderly patients with mental disorders has increased significantly. The high prevalence of pulmonary infection in the aging population has largely contributed to the increased medical burdens and mortality rate， so preventing pulmonary infection in elderly patients with mental disorders has become a critical challenge in clinical practice.www.crd.york.ac.uk/PROSPERO注册号：CRD42024553735ObjectiveTo investigate the prevalence and influencing factors of pulmonary infection in elderly patients with mental disorders， so as to provide references for preventing the occurrence of pulmonary infection in this population.MethodsOn July 1， 2024， computer searches of CNKI， China Biomedical Literature Database （CBM）， Wanfang， PubMed， Web of Science， Embase， Cochrane Library and Ovid were conducted from the inception of each database to June 2024. Two researchers independently conducted literature screening， data extraction and quality assessment. Meta-analysis was performed using Stata 16.0.ResultsA total of 17 literature （14 in Chinese， 3 in English） involving 75 724 elderly patients with mental disorders were included. Meta analysis revealed that the incidence rate of pulmonary infection in elderly patients with mental disorders was 20.8% （95% CI： 0.154~0.263）. Subgroup analysis indicated that the incidence rates of pulmonary infection among patients with dementia， schizophrenia， depression and unspecified mental disorders were 21.9% （95% CI： 0.182~0.256）， 20.6% （95% CI： 0.129~0.283）， 18.4% （95% CI： 0.136~0.232） and 5.2% （95% CI： 0.430~0.062）， respectively. In terms of influencing factors， the following were identified as risk factors for pulmonary infection in elderly patients with mental disorders： comorbid diabetes mellitus （OR=1.29， 95% CI： 1.24~1.34）， prolonged bed rest （OR=2.41， 95% CI： 2.10~2.76）， dysphagia （OR=1.76， 95% CI： 1.53~2.03）， smoking history （OR=6.27， 95% CI： 5.97~6.59）， irrational use of antibiotics （OR=2.10， 95% CI： 1.79~2.45）， hypoalbuminemia （OR=1.57， 95% CI： 1.35~1.83）， duration of illness （OR=2.05， 95% CI： 1.79~2.36）， age （OR=9.04， 95% CI： 8.44~9.68）， length of hospital stay （OR=2.68， 95% CI： 1.65~4.34）， use of proton pump inhibitors （OR=1.10， 95% CI： 1.06~1.14）， history of chronic lung disease （OR=1.50， 95% CI： 1.43~1.57）， poor oral hygiene （OR=3.66， 95% CI： 1.01~13.23）， comorbid tumors （OR=3.12， 95% CI： 2.18~4.48）， more than two somatic complications （OR=4.01， 95% CI： 1.08~14.86）， invasive procedures （OR=3.31， 95% CI： 1.81~6.04） and disorders of consciousness （OR=5.57， 95% CI： 2.18~14.24）.ConclusionElderly patients with mental disorders suffer a relatively high prevalence rate of pulmonary infection， and its prevalence rate varies among different types of mental disorders， with the highest rate being observed in patients with dementia. The factors contributing to the development of pulmonary infection are found to include age， duration of illness， smoking history， comorbid somatic complications， dysphagia， disorders of consciousness， hypoalbuminemia， prolonged bed rest， oral hygiene status， irrational use of antibiotics， use of proton pump inhibitor， length of hospital stay and invasive procedures. ［www.crd.york.ac.uk/PROSPERO number： CRD42024553735］ |
| format | Article |
| id | doaj-art-dbbdefeb3e3947ee9be9b11af7e379dd |
| institution | DOAJ |
| issn | 1007-3256 |
| language | zho |
| publishDate | 2025-04-01 |
| publisher | Editorial Office of Sichuan Mental Health |
| record_format | Article |
| series | Sichuan jingshen weisheng |
| spelling | doaj-art-dbbdefeb3e3947ee9be9b11af7e379dd2025-08-20T03:14:06ZzhoEditorial Office of Sichuan Mental HealthSichuan jingshen weisheng1007-32562025-04-0138218419210.11886/scjsws202408060011007-3256（2025）02-0184-09Prevalence and risk factors of pulmonary infection in elderly patients with mental disorders： a Meta-analysisWu Yuxiao0Xing Haoran1Bao Tianhao2Mental Health Center of Kunming Medical University， Yunnan Mental Hospital， Kunming 650000， ChinaMental Health Center of Kunming Medical University， Yunnan Mental Hospital， Kunming 650000， ChinaMental Health Center of Kunming Medical University， Yunnan Mental Hospital， Kunming 650000， ChinaBackgroundWith the exacerbation of population aging， the number of elderly patients with mental disorders has increased significantly. The high prevalence of pulmonary infection in the aging population has largely contributed to the increased medical burdens and mortality rate， so preventing pulmonary infection in elderly patients with mental disorders has become a critical challenge in clinical practice.www.crd.york.ac.uk/PROSPERO注册号：CRD42024553735ObjectiveTo investigate the prevalence and influencing factors of pulmonary infection in elderly patients with mental disorders， so as to provide references for preventing the occurrence of pulmonary infection in this population.MethodsOn July 1， 2024， computer searches of CNKI， China Biomedical Literature Database （CBM）， Wanfang， PubMed， Web of Science， Embase， Cochrane Library and Ovid were conducted from the inception of each database to June 2024. Two researchers independently conducted literature screening， data extraction and quality assessment. Meta-analysis was performed using Stata 16.0.ResultsA total of 17 literature （14 in Chinese， 3 in English） involving 75 724 elderly patients with mental disorders were included. Meta analysis revealed that the incidence rate of pulmonary infection in elderly patients with mental disorders was 20.8% （95% CI： 0.154~0.263）. Subgroup analysis indicated that the incidence rates of pulmonary infection among patients with dementia， schizophrenia， depression and unspecified mental disorders were 21.9% （95% CI： 0.182~0.256）， 20.6% （95% CI： 0.129~0.283）， 18.4% （95% CI： 0.136~0.232） and 5.2% （95% CI： 0.430~0.062）， respectively. In terms of influencing factors， the following were identified as risk factors for pulmonary infection in elderly patients with mental disorders： comorbid diabetes mellitus （OR=1.29， 95% CI： 1.24~1.34）， prolonged bed rest （OR=2.41， 95% CI： 2.10~2.76）， dysphagia （OR=1.76， 95% CI： 1.53~2.03）， smoking history （OR=6.27， 95% CI： 5.97~6.59）， irrational use of antibiotics （OR=2.10， 95% CI： 1.79~2.45）， hypoalbuminemia （OR=1.57， 95% CI： 1.35~1.83）， duration of illness （OR=2.05， 95% CI： 1.79~2.36）， age （OR=9.04， 95% CI： 8.44~9.68）， length of hospital stay （OR=2.68， 95% CI： 1.65~4.34）， use of proton pump inhibitors （OR=1.10， 95% CI： 1.06~1.14）， history of chronic lung disease （OR=1.50， 95% CI： 1.43~1.57）， poor oral hygiene （OR=3.66， 95% CI： 1.01~13.23）， comorbid tumors （OR=3.12， 95% CI： 2.18~4.48）， more than two somatic complications （OR=4.01， 95% CI： 1.08~14.86）， invasive procedures （OR=3.31， 95% CI： 1.81~6.04） and disorders of consciousness （OR=5.57， 95% CI： 2.18~14.24）.ConclusionElderly patients with mental disorders suffer a relatively high prevalence rate of pulmonary infection， and its prevalence rate varies among different types of mental disorders， with the highest rate being observed in patients with dementia. The factors contributing to the development of pulmonary infection are found to include age， duration of illness， smoking history， comorbid somatic complications， dysphagia， disorders of consciousness， hypoalbuminemia， prolonged bed rest， oral hygiene status， irrational use of antibiotics， use of proton pump inhibitor， length of hospital stay and invasive procedures. ［www.crd.york.ac.uk/PROSPERO number： CRD42024553735］http://www.psychjm.net.cn/scjswszz/ch/reader/view_abstract.aspx?file_no=202502014&flag=1elderlymental disorderspulmonary infectionrisk factorsmeta-analysis |
| spellingShingle | Wu Yuxiao Xing Haoran Bao Tianhao Prevalence and risk factors of pulmonary infection in elderly patients with mental disorders： a Meta-analysis Sichuan jingshen weisheng elderly mental disorders pulmonary infection risk factors meta-analysis |
| title | Prevalence and risk factors of pulmonary infection in elderly patients with mental disorders： a Meta-analysis |
| title_full | Prevalence and risk factors of pulmonary infection in elderly patients with mental disorders： a Meta-analysis |
| title_fullStr | Prevalence and risk factors of pulmonary infection in elderly patients with mental disorders： a Meta-analysis |
| title_full_unstemmed | Prevalence and risk factors of pulmonary infection in elderly patients with mental disorders： a Meta-analysis |
| title_short | Prevalence and risk factors of pulmonary infection in elderly patients with mental disorders： a Meta-analysis |
| title_sort | prevalence and risk factors of pulmonary infection in elderly patients with mental disorders a meta analysis |
| topic | elderly mental disorders pulmonary infection risk factors meta-analysis |
| url | http://www.psychjm.net.cn/scjswszz/ch/reader/view_abstract.aspx?file_no=202502014&flag=1 |
| work_keys_str_mv | AT wuyuxiao prevalenceandriskfactorsofpulmonaryinfectioninelderlypatientswithmentaldisordersametaanalysis AT xinghaoran prevalenceandriskfactorsofpulmonaryinfectioninelderlypatientswithmentaldisordersametaanalysis AT baotianhao prevalenceandriskfactorsofpulmonaryinfectioninelderlypatientswithmentaldisordersametaanalysis |