Study on the mechanism of hsa_circ_0074763 regulating the miR-3667-3P/ACSL4 axis in liver fibrosis

Study on the mechanism of hsa_circ_0074763 regulating the miR-3667-3P/ACSL4 axis in liver fibrosis

Abstract This study aimed to investigate the involvement of hsa_circ_0074763 in the activation of HSCs (hepatic stellate cells ) and liver fibrosis. Additionally, it aimed to conduct a preliminary analysis of the molecular mechanism targeting miR-3667-3p/ACSL4 (Long-chain acyl-CoA synthetase 4), the...

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Bibliographic Details
Main Authors: Yanling Cheng, Tiantian Song, Jiachen Yao, Qirong Wang, Chunyan Meng, Fumin Feng
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
CircRNA
MiRNA
Liver fibrosis
Ferroptosis
Online Access:https://doi.org/10.1038/s41598-025-91393-2
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