Elevated FDG uptake in non-tumorous lung regions does not predict immune checkpoint inhibitor–related pneumonitis in lung cancer patients

Elevated FDG uptake in non-tumorous lung regions does not predict immune checkpoint inhibitor–related pneumonitis in lung cancer patients

BackgroundPredictors for checkpoint inhibitor-related pneumonitis (cinrPneumonitis) are desperately needed. This study aimed to investigate the pretreatment standardized uptake value (SUV) on [18F]FDG-PET/CT of non-tumorous lung tissue as a predictive imaging marker for the development of cinrPneumo...

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Main Authors: Friederike Völter, Lukas Wehlte, Blerina Resuli, Julia Walter, Lea Daisenberger, Maria Ingenerf, Maurice Heimer, Matthias Brendel, Gabriel T. Sheikh, Lena M. Unterrainer, Diego Kauffmann-Guerrero, Thomas Pfluger, Lucie Heinzerling, Amanda Tufman
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
Subjects:
lung cancer
NSCLC
SCLC
[18F]FDG-PET/CT
standardized uptake value
checkpoint inhibitor therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1563030/full
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