FCRL3 genetic variants drive autoimmune pathogenesis in multiple sclerosis and neuromyelitis optica spectrum disorders

FCRL3 genetic variants drive autoimmune pathogenesis in multiple sclerosis and neuromyelitis optica spectrum disorders

ObjectiveThis study aims to investigate the association of Fc receptor-like 3 (FCRL3) gene variants with multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) in a Chinese population cohort.MethodsIn Stage 1, 154 MS patients, 109 NMOSD patients, and 301 normal controls were recr...

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Bibliographic Details
Main Authors: Hui-Fen Huang, Qi-Bing Liu, Yong-Feng Xu, Gui-Xian Zhao, Hai-Peng Liu, Hao Yu, Zhi-Ying Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Neurology
Subjects:
multiple sclerosis
neuromyelitis optica spectrum disorders
FCRL3
variant
association
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1552149/full
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