Analysis of Transcriptional Signatures in Response to Listeria monocytogenes Infection Reveals Temporal Changes That Result from Type I Interferon Signaling.

Analysis of Transcriptional Signatures in Response to Listeria monocytogenes Infection Reveals Temporal Changes That Result from Type I Interferon Signaling.

Analysis of the mouse transcriptional response to Listeria monocytogenes infection reveals that a large set of genes are perturbed in both blood and tissue and that these transcriptional responses are enriched for pathways of the immune response. Further we identified enrichment for both type I and...

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Main Authors: Jonathan M Pitt, Simon Blankley, Krzysztof Potempa, Christine M Graham, Lucia Moreira-Teixeira, Finlay W McNab, Ashleigh Howes, Evangelos Stavropoulos, Virginia Pascual, Jacques Banchereau, Damien Chaussabel, Anne O'Garra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0150251
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