Smooth Muscle Cell Alignment and Phenotype Control by Melt Spun Polycaprolactone Fibers for Seeding of Tissue Engineered Blood Vessels
A method has been developed to induce and retain a contractile phenotype for vascular smooth muscle cells, as the first step towards the development of a biomimetic blood vessel construct with minimal compliance mismatch. Melt spun PCL fibers were deposited on a mandrel to form aligned fibers of 10 ...
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Main Authors: | Animesh Agrawal, Bae Hoon Lee, Scott A. Irvine, Jia An, Ramya Bhuthalingam, Vaishali Singh, Kok Yao Low, Chee Kai Chua, Subbu S. Venkatraman |
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Format: | Article |
Language: | English |
Published: |
Wiley
2015-01-01
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Series: | International Journal of Biomaterials |
Online Access: | http://dx.doi.org/10.1155/2015/434876 |
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