Factors predicting early discontinuation of methotrexate as a first-line treatment for rheumatoid arthritis in Italy: Results from the GISEA registry

Factors predicting early discontinuation of methotrexate as a first-line treatment for rheumatoid arthritis in Italy: Results from the GISEA registry

Objective: Despite the well-established efficacy of methotrexate (MTX) in rheumatoid arthritis (RA), monotherapy is not sufficient in almost half of patients. The aim of this registry-based study was to detect possible predictive factors for the early failure of MTX as a first-line treatment in earl...

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Main Authors: Andreina Manfredi, Marco Sebastiani, Florenzo Iannone, Elisa Gremese, Alessandra Bortoluzzi, Ennio Favalli, Roberto Gorla, Fausto Salaffi, Enrico Fusaro, Rosario Foti, Luca Cantarini, Roberto Caporali, Alberto Cauli, Stefano Alivernini, Francesco Paolo Cantatore, Antonio Carletto, Fabrizio Conti, Salvatore D'Angelo1, Oscar Epis, Roberta Ramonda, Antonio Marchesoni, Gianfranco Ferraccioli, Giovanni Lapadula
Format: Article
Language:English
Published: SAGE Publishing 2019-01-01
Series:Indian Journal of Rheumatology
Subjects:
anti-citrullinated protein antibodies
methotrexate
rheumatoid arthritis
treatment failure
Online Access:http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2019;volume=14;issue=4;spage=271;epage=276;aulast=Manfredi
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