Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity

We present a case of a nearly 3-year-old girl who was admitted to hospital due to severe hypernatremia (196 mmol/l). Her medical history included central hypothyreosis and growth hormone deficiency. Rehydration and normalization of sodium was achieved according to guidelines. On the fourth day of ho...

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Main Authors: Jan-Niclas Schwade, Lior Haftel, Lars Rühe, Matthias Endmann
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2019/7381597
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author Jan-Niclas Schwade
Lior Haftel
Lars Rühe
Matthias Endmann
author_facet Jan-Niclas Schwade
Lior Haftel
Lars Rühe
Matthias Endmann
author_sort Jan-Niclas Schwade
collection DOAJ
description We present a case of a nearly 3-year-old girl who was admitted to hospital due to severe hypernatremia (196 mmol/l). Her medical history included central hypothyreosis and growth hormone deficiency. Rehydration and normalization of sodium was achieved according to guidelines. On the fourth day of hospitalization, the patient developed tremor, ataxia, and rigor. Cranial magnetic resonance imaging (cMRI) was performed and (mis)interpreted for meningoencephalitis, with corresponding diagnostic and therapeutic implications. The patient had extrapontine myelinolysis. The child recovered completely after hospitalization for nearly 2 weeks.
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institution Kabale University
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language English
publishDate 2019-01-01
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series Case Reports in Pediatrics
spelling doaj-art-db966914460d4fe3b81ab959cde3ca4d2025-02-03T05:53:55ZengWileyCase Reports in Pediatrics2090-68032090-68112019-01-01201910.1155/2019/73815977381597Extrapontine Myelinolysis following Extreme Hypernatremia and HyperosmolarityJan-Niclas Schwade0Lior Haftel1Lars Rühe2Matthias Endmann3Klinik für Kinder-und Jugendmedizin, Evangelisches Krankenhaus Lippstadt, Wiedenbrückerstr. 33, 59555 Lippstadt, GermanyKlinik für Kinder-und Jugendmedizin, Evangelisches Krankenhaus Lippstadt, Wiedenbrückerstr. 33, 59555 Lippstadt, GermanyRadiologische Gemeinschaftspraxis am Evangelischen Krankenhaus Lippstadt, Wiedenbrückerstr. 33, 59555 Lippstadt, GermanyKlinik für Kinder-und Jugendmedizin, Evangelisches Krankenhaus Lippstadt, Wiedenbrückerstr. 33, 59555 Lippstadt, GermanyWe present a case of a nearly 3-year-old girl who was admitted to hospital due to severe hypernatremia (196 mmol/l). Her medical history included central hypothyreosis and growth hormone deficiency. Rehydration and normalization of sodium was achieved according to guidelines. On the fourth day of hospitalization, the patient developed tremor, ataxia, and rigor. Cranial magnetic resonance imaging (cMRI) was performed and (mis)interpreted for meningoencephalitis, with corresponding diagnostic and therapeutic implications. The patient had extrapontine myelinolysis. The child recovered completely after hospitalization for nearly 2 weeks.http://dx.doi.org/10.1155/2019/7381597
spellingShingle Jan-Niclas Schwade
Lior Haftel
Lars Rühe
Matthias Endmann
Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity
Case Reports in Pediatrics
title Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity
title_full Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity
title_fullStr Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity
title_full_unstemmed Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity
title_short Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity
title_sort extrapontine myelinolysis following extreme hypernatremia and hyperosmolarity
url http://dx.doi.org/10.1155/2019/7381597
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AT liorhaftel extrapontinemyelinolysisfollowingextremehypernatremiaandhyperosmolarity
AT larsruhe extrapontinemyelinolysisfollowingextremehypernatremiaandhyperosmolarity
AT matthiasendmann extrapontinemyelinolysisfollowingextremehypernatremiaandhyperosmolarity