METTL3 promotes an immunosuppressive microenvironment in bladder cancer via m6A-dependent CXCL5/CCL5 regulation

METTL3 promotes an immunosuppressive microenvironment in bladder cancer via m6A-dependent CXCL5/CCL5 regulation

Background Bladder cancer (BLCA) is a challenging malignancy with a poor prognosis, particularly in muscle-invasive cases. Despite recent advancements in immunotherapy, response rates remain suboptimal. This study investigates the role of METTL3, an m6A RNA methylation “writer,” in regulating the im...

Full description

Saved in:
Bibliographic Details
Main Authors: Jian Wu, Kun Tang, Yu He, Zhihua Wang, Zhiqiang Chen, Ding Xia, Yonghua Tong, Qiu Huang, Haojie Shang, Ejun Peng, Xiaoyu Liang
Format: Article
Language:English
Published: BMJ Publishing Group 2025-04-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/4/e011108.full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items