PET CT Imaging with FDG in the Therapeutical Management of Locally Advanced Cervical Cancer Diagnosed in a 43-Year-Old Patient: Case Report and Review of the Literature

<b>Background:</b> Cervical cancer is the most important cancer type found in women throughout the world. Numerous research studies are being performed to investigate the effectiveness of different strategies for the imaging and treatment of locally advanced cervical cancer, which are sh...

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Main Authors: Ottó Molnar, Simona Mihuțiu, Oreste Mihai Straciuc, Alexandra Vesa, Liviu Lazar
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Biomedicines
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Online Access:https://www.mdpi.com/2227-9059/13/1/83
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author Ottó Molnar
Simona Mihuțiu
Oreste Mihai Straciuc
Alexandra Vesa
Liviu Lazar
author_facet Ottó Molnar
Simona Mihuțiu
Oreste Mihai Straciuc
Alexandra Vesa
Liviu Lazar
author_sort Ottó Molnar
collection DOAJ
description <b>Background:</b> Cervical cancer is the most important cancer type found in women throughout the world. Numerous research studies are being performed to investigate the effectiveness of different strategies for the imaging and treatment of locally advanced cervical cancer, which are showing favorable outcomes. Brachytherapy is characterized by the application of very high radiation doses to target tumor cells with the least exposure to normal tissues. <b>Methods:</b> In the present case study, we report a 43-year-old female patient suffering from cervical cancer belonging to urban origin, with no personal pathological history, who presented herself to the gynecology department of the Bihor County Emergency Clinical hospital with vaginal bleeding. The histopathological examination of the cervix showed squamous cell carcinoma. The treatment was performed with neoadjuvant chemotherapy and concurrent chemoradiotherapy. <b>Results:</b> According to the clinical and histopathological examination, a diagnosis of non-keratinizing squamous carcinoma of the uterine cervix at FIGO stage III C1 was established. Radio-chemotherapy was performed, as well as periodic imaging assessments with a CT of the chest, pelvis, and abdomen, without local and distant relapse. FDG PET imaging was performed for the management and follow-up of cervical cancer by retrieving the SUVmax value. <b>Conclusions:</b> The post-therapeutic complications are represented by the vaginal stenosis installed 6 months after the end of the radiotherapeutic treatment.
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spelling doaj-art-db87c754489942d0bd422adc2fbff2842025-01-24T13:23:57ZengMDPI AGBiomedicines2227-90592025-01-011318310.3390/biomedicines13010083PET CT Imaging with FDG in the Therapeutical Management of Locally Advanced Cervical Cancer Diagnosed in a 43-Year-Old Patient: Case Report and Review of the LiteratureOttó Molnar0Simona Mihuțiu1Oreste Mihai Straciuc2Alexandra Vesa3Liviu Lazar4Doctoral Studies Department, Biomedical Science, 410087 Oradea, RomaniaDepartment of Medicine-Psycho-Neuroscience and Recovery, Faculty of Medicine and Pharmacy, 410073 Oradea, RomaniaDoctoral Studies Department, Biomedical Science, 410087 Oradea, RomaniaDepartment of Morphological Sciences, Faculty of Medicine and Pharamacy, 410073 Oradea, RomaniaDoctoral Studies Department, Biomedical Science, 410087 Oradea, Romania<b>Background:</b> Cervical cancer is the most important cancer type found in women throughout the world. Numerous research studies are being performed to investigate the effectiveness of different strategies for the imaging and treatment of locally advanced cervical cancer, which are showing favorable outcomes. Brachytherapy is characterized by the application of very high radiation doses to target tumor cells with the least exposure to normal tissues. <b>Methods:</b> In the present case study, we report a 43-year-old female patient suffering from cervical cancer belonging to urban origin, with no personal pathological history, who presented herself to the gynecology department of the Bihor County Emergency Clinical hospital with vaginal bleeding. The histopathological examination of the cervix showed squamous cell carcinoma. The treatment was performed with neoadjuvant chemotherapy and concurrent chemoradiotherapy. <b>Results:</b> According to the clinical and histopathological examination, a diagnosis of non-keratinizing squamous carcinoma of the uterine cervix at FIGO stage III C1 was established. Radio-chemotherapy was performed, as well as periodic imaging assessments with a CT of the chest, pelvis, and abdomen, without local and distant relapse. FDG PET imaging was performed for the management and follow-up of cervical cancer by retrieving the SUVmax value. <b>Conclusions:</b> The post-therapeutic complications are represented by the vaginal stenosis installed 6 months after the end of the radiotherapeutic treatment.https://www.mdpi.com/2227-9059/13/1/83FDG-PET/CTSUVmaxLACCfluorodeoxyglucose F-18cervical cancerdiagnosis
spellingShingle Ottó Molnar
Simona Mihuțiu
Oreste Mihai Straciuc
Alexandra Vesa
Liviu Lazar
PET CT Imaging with FDG in the Therapeutical Management of Locally Advanced Cervical Cancer Diagnosed in a 43-Year-Old Patient: Case Report and Review of the Literature
Biomedicines
FDG-PET/CT
SUVmax
LACC
fluorodeoxyglucose F-18
cervical cancer
diagnosis
title PET CT Imaging with FDG in the Therapeutical Management of Locally Advanced Cervical Cancer Diagnosed in a 43-Year-Old Patient: Case Report and Review of the Literature
title_full PET CT Imaging with FDG in the Therapeutical Management of Locally Advanced Cervical Cancer Diagnosed in a 43-Year-Old Patient: Case Report and Review of the Literature
title_fullStr PET CT Imaging with FDG in the Therapeutical Management of Locally Advanced Cervical Cancer Diagnosed in a 43-Year-Old Patient: Case Report and Review of the Literature
title_full_unstemmed PET CT Imaging with FDG in the Therapeutical Management of Locally Advanced Cervical Cancer Diagnosed in a 43-Year-Old Patient: Case Report and Review of the Literature
title_short PET CT Imaging with FDG in the Therapeutical Management of Locally Advanced Cervical Cancer Diagnosed in a 43-Year-Old Patient: Case Report and Review of the Literature
title_sort pet ct imaging with fdg in the therapeutical management of locally advanced cervical cancer diagnosed in a 43 year old patient case report and review of the literature
topic FDG-PET/CT
SUVmax
LACC
fluorodeoxyglucose F-18
cervical cancer
diagnosis
url https://www.mdpi.com/2227-9059/13/1/83
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