miRNA panel from HER2+ and CD24+ plasma extracellular vesicle subpopulations as biomarkers of early-stage breast cancer

miRNA panel from HER2+ and CD24+ plasma extracellular vesicle subpopulations as biomarkers of early-stage breast cancer

Abstract Background Mammography screening has improved early breast cancer detection, leading to reduced mortality and lower rates of advanced breast cancer. However, mammography has a high false positive rate that results in over a million invasive breast biopsies of benign lesions in the US each y...

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Bibliographic Details
Main Authors: Griffin B. Spychalski, Andrew A. Lin, Stephanie J. Yang, Hanfei Shen, Jean Rosario, Kyle Tien, Kate French, Miriyam Ghali, Stephanie Yee, Melinda Yin, Michael D. Feldman, Emily F. Conant, Susan P. Weinstein, Erica L. Carpenter, David Issadore, Anupma Nayak
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Breast Cancer Research
Subjects:
Early detection biomarkers
BI-RADS 4 breast lesions
Extracellular vesicles
Liquid biopsy
MiRNA sequencing
Online Access:https://doi.org/10.1186/s13058-025-02029-2
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