Generation of human iPSC-derived pancreatic organoids to study pancreas development and disease [version 1; peer review: 2 approved, 2 approved with reservations]
The pancreas has vital endocrine and exocrine functions that can be affected by life-threatening diseases such as diabetes and pancreatic cancer. Although animal models are essential for understanding pancreatic development and disease, they are limited by their low throughput and major species-spec...
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| Main Authors: | Francesca Maria Spagnoli, Abigail Isaacson, Jean-Francois Darrigrand |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2025-06-01
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| Series: | F1000Research |
| Subjects: | |
| Online Access: | https://f1000research.com/articles/14-575/v1 |
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