Atypical imaging presentation of hepatocellular carcinoma - Case series

Hepatocellular carcinoma (HCC), the most common primary liver tumor, significantly contributes to cancer-related mortality worldwide. This case series investigated HCC imaging presentations, including portal vein tumor thrombus, multifocal HCC, cirrhotomimetic diffuse infiltrative HCC, metastasis to...

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Main Authors: Divya S, Geetha G, Ashwin Kumar A
Format: Article
Language:English
Published: Manipal College of Medical Sciences, Pokhara 2025-02-01
Series:Asian Journal of Medical Sciences
Subjects:
Online Access:https://ajmsjournal.info/index.php/AJMS/article/view/4390
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author Divya S
Geetha G
Ashwin Kumar A
author_facet Divya S
Geetha G
Ashwin Kumar A
author_sort Divya S
collection DOAJ
description Hepatocellular carcinoma (HCC), the most common primary liver tumor, significantly contributes to cancer-related mortality worldwide. This case series investigated HCC imaging presentations, including portal vein tumor thrombus, multifocal HCC, cirrhotomimetic diffuse infiltrative HCC, metastasis to various organs, HCC with capsular rupture and hemoperitoneum, and unusual features like a fatty metamorphosis. Imaging plays a crucial role in HCC detection, diagnosis, staging, and posttreatment monitoring, and ultrasonography is recommended for screening and triple-phase computed tomography, which is essential for characterization and staging. Typical imaging features include arterial phase hyperenhancement, washout in later phases, and tumor capsule. Recognizing imaging presentations is vital for accurate diagnosis and management, as HCC complications indicate advanced disease and poor prognosis. This series highlights HCC’s diverse imaging spectrum of HCC and emphasizes the importance of identifying atypical presentations for timely diagnosis and appropriate management.
format Article
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institution Kabale University
issn 2467-9100
2091-0576
language English
publishDate 2025-02-01
publisher Manipal College of Medical Sciences, Pokhara
record_format Article
series Asian Journal of Medical Sciences
spelling doaj-art-db751d0acad5421285de400b565c96cf2025-02-01T12:43:23ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762025-02-01162139143https://doi.org/10.71152/ajms.v16i2.4390Atypical imaging presentation of hepatocellular carcinoma - Case seriesDivya S 0https://orcid.org/0009-0005-1550-6092Geetha G 1https://orcid.org/0009-0008-8639-1626Ashwin Kumar A 2https://orcid.org/0000-0001-5640-2656Assistant Professor, Department of Radiology, Barnard Institute of Radiology, Madras Medical College, Chennai, Tamil Nadu, India Associate Professor, Department of Radiology, Barnard Institute of Radiology, Madras Medical College, Chennai, Tamil Nadu, India Associate Professor, Department of Radiology, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India Hepatocellular carcinoma (HCC), the most common primary liver tumor, significantly contributes to cancer-related mortality worldwide. This case series investigated HCC imaging presentations, including portal vein tumor thrombus, multifocal HCC, cirrhotomimetic diffuse infiltrative HCC, metastasis to various organs, HCC with capsular rupture and hemoperitoneum, and unusual features like a fatty metamorphosis. Imaging plays a crucial role in HCC detection, diagnosis, staging, and posttreatment monitoring, and ultrasonography is recommended for screening and triple-phase computed tomography, which is essential for characterization and staging. Typical imaging features include arterial phase hyperenhancement, washout in later phases, and tumor capsule. Recognizing imaging presentations is vital for accurate diagnosis and management, as HCC complications indicate advanced disease and poor prognosis. This series highlights HCC’s diverse imaging spectrum of HCC and emphasizes the importance of identifying atypical presentations for timely diagnosis and appropriate management.https://ajmsjournal.info/index.php/AJMS/article/view/4390hepatocellular carcinoma; atypical imaging presentations; portal vein tumor thrombus
spellingShingle Divya S
Geetha G
Ashwin Kumar A
Atypical imaging presentation of hepatocellular carcinoma - Case series
Asian Journal of Medical Sciences
hepatocellular carcinoma; atypical imaging presentations; portal vein tumor thrombus
title Atypical imaging presentation of hepatocellular carcinoma - Case series
title_full Atypical imaging presentation of hepatocellular carcinoma - Case series
title_fullStr Atypical imaging presentation of hepatocellular carcinoma - Case series
title_full_unstemmed Atypical imaging presentation of hepatocellular carcinoma - Case series
title_short Atypical imaging presentation of hepatocellular carcinoma - Case series
title_sort atypical imaging presentation of hepatocellular carcinoma case series
topic hepatocellular carcinoma; atypical imaging presentations; portal vein tumor thrombus
url https://ajmsjournal.info/index.php/AJMS/article/view/4390
work_keys_str_mv AT divyas atypicalimagingpresentationofhepatocellularcarcinomacaseseries
AT geethag atypicalimagingpresentationofhepatocellularcarcinomacaseseries
AT ashwinkumara atypicalimagingpresentationofhepatocellularcarcinomacaseseries