Lentinan-functionalized PBAE-G-nanodiamonds as an adjuvant to induce cGAS-STING pathway-mediated macrophage activation and immune enhancement

A series of biodegradable nanoparticle-based drug delivery systems have been designed utilizing poly(β-amino ester)-guanidine-phenylboronic acid (PBAE-G) polymers. In this study, a novel Lentinan-Functionalized PBAE-G-nanodiamond system was developed to carry ovalbumin (LNT-PBAE-G-ND@OVA). The impac...

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Bibliographic Details
Main Authors: Zhiqiang Zhang, Li Wang, Xia Ma, Hui Wang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Pharmaceutical Analysis
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Online Access:http://www.sciencedirect.com/science/article/pii/S2095177923002952
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