Scalable in vitro production of defined mouse erythroblasts.

Scalable in vitro production of defined mouse erythroblasts.

Mouse embryonic stem cells (mESCs) can be manipulated in vitro to recapitulate the process of erythropoiesis, during which multipotent cells undergo lineage specification, differentiation and maturation to produce erythroid cells. Although useful for identifying specific progenitors and precursors,...

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Bibliographic Details
Main Authors: Helena S Francis, Caroline L Harold, Robert A Beagrie, Andrew J King, Matthew E Gosden, Joseph W Blayney, Danuta M Jeziorska, Christian Babbs, Douglas R Higgs, Mira T Kassouf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0261950&type=printable
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