Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer
A 30-year-old male with hereditary angioedema (HAE) due to C1 inhibitor deficiency was admitted to the Emergency Department (ED) due to severe abdominal pain lasting for 3 hs with severe bloating and weakness. pdC1INH and fluids were applied as usual and the patient was discharged with feeling bette...
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Termedia Publishing House
2024-02-01
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Series: | Alergologia Polska |
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Online Access: | https://www.termedia.pl/Abdominal-attack-in-a-patient-with-hereditary-angioedema-due-to-C1-inhibitor-deficiency-complicated-by-a-perforated-peptic-ulcer,123,52432,1,1.html |
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author | Piotr Obtulowicz Marcin Stobiecki Wojciech Dyga Tadeusz Popiela Krystyna Obtulowicz |
author_facet | Piotr Obtulowicz Marcin Stobiecki Wojciech Dyga Tadeusz Popiela Krystyna Obtulowicz |
author_sort | Piotr Obtulowicz |
collection | DOAJ |
description | A 30-year-old male with hereditary angioedema (HAE) due to C1 inhibitor deficiency was admitted to the Emergency Department (ED) due to severe abdominal pain lasting for 3 hs with severe bloating and weakness. pdC1INH and fluids were applied as usual and the patient was discharged with feeling better. A few hours later abdominal symptoms recurred and erythema appeared, thus the allergy to antispasmodic drug taken by the patient was suspected. In the ED, the patient received anti-allergic treatment and was discharged again. After 3 h severe abdominal symptoms returned with fever. The patient was readmitted to the ED with peritoneal symptoms. Abdominal X-ray confirmed digestive tract perforation. Laparotomy revealed perforation of the chronic duodenal ulcer. In conclusion, we indicate that a HAE patient with an abdominal pain not resolving after usually effective treatment, should be hospitalized and monitored. Differential diagnosis of reasons other than HAE attack should be made. |
format | Article |
id | doaj-art-db431d3869974e5c8688dfd519e47261 |
institution | Kabale University |
issn | 2353-3854 2391-6052 |
language | English |
publishDate | 2024-02-01 |
publisher | Termedia Publishing House |
record_format | Article |
series | Alergologia Polska |
spelling | doaj-art-db431d3869974e5c8688dfd519e472612025-01-27T10:33:53ZengTermedia Publishing HouseAlergologia Polska2353-38542391-60522024-02-01111808310.5114/pja.2024.13554852432Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcerPiotr ObtulowiczMarcin StobieckiWojciech DygaTadeusz PopielaKrystyna ObtulowiczA 30-year-old male with hereditary angioedema (HAE) due to C1 inhibitor deficiency was admitted to the Emergency Department (ED) due to severe abdominal pain lasting for 3 hs with severe bloating and weakness. pdC1INH and fluids were applied as usual and the patient was discharged with feeling better. A few hours later abdominal symptoms recurred and erythema appeared, thus the allergy to antispasmodic drug taken by the patient was suspected. In the ED, the patient received anti-allergic treatment and was discharged again. After 3 h severe abdominal symptoms returned with fever. The patient was readmitted to the ED with peritoneal symptoms. Abdominal X-ray confirmed digestive tract perforation. Laparotomy revealed perforation of the chronic duodenal ulcer. In conclusion, we indicate that a HAE patient with an abdominal pain not resolving after usually effective treatment, should be hospitalized and monitored. Differential diagnosis of reasons other than HAE attack should be made.https://www.termedia.pl/Abdominal-attack-in-a-patient-with-hereditary-angioedema-due-to-C1-inhibitor-deficiency-complicated-by-a-perforated-peptic-ulcer,123,52432,1,1.htmlabdominal imaging hereditary angioedema c1 inhibitor deficiency angioedema |
spellingShingle | Piotr Obtulowicz Marcin Stobiecki Wojciech Dyga Tadeusz Popiela Krystyna Obtulowicz Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer Alergologia Polska abdominal imaging hereditary angioedema c1 inhibitor deficiency angioedema |
title | Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer |
title_full | Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer |
title_fullStr | Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer |
title_full_unstemmed | Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer |
title_short | Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer |
title_sort | abdominal attack in a patient with hereditary angioedema due to c1 inhibitor deficiency complicated by a perforated peptic ulcer |
topic | abdominal imaging hereditary angioedema c1 inhibitor deficiency angioedema |
url | https://www.termedia.pl/Abdominal-attack-in-a-patient-with-hereditary-angioedema-due-to-C1-inhibitor-deficiency-complicated-by-a-perforated-peptic-ulcer,123,52432,1,1.html |
work_keys_str_mv | AT piotrobtulowicz abdominalattackinapatientwithhereditaryangioedemaduetoc1inhibitordeficiencycomplicatedbyaperforatedpepticulcer AT marcinstobiecki abdominalattackinapatientwithhereditaryangioedemaduetoc1inhibitordeficiencycomplicatedbyaperforatedpepticulcer AT wojciechdyga abdominalattackinapatientwithhereditaryangioedemaduetoc1inhibitordeficiencycomplicatedbyaperforatedpepticulcer AT tadeuszpopiela abdominalattackinapatientwithhereditaryangioedemaduetoc1inhibitordeficiencycomplicatedbyaperforatedpepticulcer AT krystynaobtulowicz abdominalattackinapatientwithhereditaryangioedemaduetoc1inhibitordeficiencycomplicatedbyaperforatedpepticulcer |