Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer

A 30-year-old male with hereditary angioedema (HAE) due to C1 inhibitor deficiency was admitted to the Emergency Department (ED) due to severe abdominal pain lasting for 3 hs with severe bloating and weakness. pdC1INH and fluids were applied as usual and the patient was discharged with feeling bette...

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Main Authors: Piotr Obtulowicz, Marcin Stobiecki, Wojciech Dyga, Tadeusz Popiela, Krystyna Obtulowicz
Format: Article
Language:English
Published: Termedia Publishing House 2024-02-01
Series:Alergologia Polska
Subjects:
Online Access:https://www.termedia.pl/Abdominal-attack-in-a-patient-with-hereditary-angioedema-due-to-C1-inhibitor-deficiency-complicated-by-a-perforated-peptic-ulcer,123,52432,1,1.html
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author Piotr Obtulowicz
Marcin Stobiecki
Wojciech Dyga
Tadeusz Popiela
Krystyna Obtulowicz
author_facet Piotr Obtulowicz
Marcin Stobiecki
Wojciech Dyga
Tadeusz Popiela
Krystyna Obtulowicz
author_sort Piotr Obtulowicz
collection DOAJ
description A 30-year-old male with hereditary angioedema (HAE) due to C1 inhibitor deficiency was admitted to the Emergency Department (ED) due to severe abdominal pain lasting for 3 hs with severe bloating and weakness. pdC1INH and fluids were applied as usual and the patient was discharged with feeling better. A few hours later abdominal symptoms recurred and erythema appeared, thus the allergy to antispasmodic drug taken by the patient was suspected. In the ED, the patient received anti-allergic treatment and was discharged again. After 3 h severe abdominal symptoms returned with fever. The patient was readmitted to the ED with peritoneal symptoms. Abdominal X-ray confirmed digestive tract perforation. Laparotomy revealed perforation of the chronic duodenal ulcer. In conclusion, we indicate that a HAE patient with an abdominal pain not resolving after usually effective treatment, should be hospitalized and monitored. Differential diagnosis of reasons other than HAE attack should be made.
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institution Kabale University
issn 2353-3854
2391-6052
language English
publishDate 2024-02-01
publisher Termedia Publishing House
record_format Article
series Alergologia Polska
spelling doaj-art-db431d3869974e5c8688dfd519e472612025-01-27T10:33:53ZengTermedia Publishing HouseAlergologia Polska2353-38542391-60522024-02-01111808310.5114/pja.2024.13554852432Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcerPiotr ObtulowiczMarcin StobieckiWojciech DygaTadeusz PopielaKrystyna ObtulowiczA 30-year-old male with hereditary angioedema (HAE) due to C1 inhibitor deficiency was admitted to the Emergency Department (ED) due to severe abdominal pain lasting for 3 hs with severe bloating and weakness. pdC1INH and fluids were applied as usual and the patient was discharged with feeling better. A few hours later abdominal symptoms recurred and erythema appeared, thus the allergy to antispasmodic drug taken by the patient was suspected. In the ED, the patient received anti-allergic treatment and was discharged again. After 3 h severe abdominal symptoms returned with fever. The patient was readmitted to the ED with peritoneal symptoms. Abdominal X-ray confirmed digestive tract perforation. Laparotomy revealed perforation of the chronic duodenal ulcer. In conclusion, we indicate that a HAE patient with an abdominal pain not resolving after usually effective treatment, should be hospitalized and monitored. Differential diagnosis of reasons other than HAE attack should be made.https://www.termedia.pl/Abdominal-attack-in-a-patient-with-hereditary-angioedema-due-to-C1-inhibitor-deficiency-complicated-by-a-perforated-peptic-ulcer,123,52432,1,1.htmlabdominal imaging hereditary angioedema c1 inhibitor deficiency angioedema
spellingShingle Piotr Obtulowicz
Marcin Stobiecki
Wojciech Dyga
Tadeusz Popiela
Krystyna Obtulowicz
Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer
Alergologia Polska
abdominal imaging
hereditary angioedema
c1 inhibitor deficiency
angioedema
title Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer
title_full Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer
title_fullStr Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer
title_full_unstemmed Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer
title_short Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer
title_sort abdominal attack in a patient with hereditary angioedema due to c1 inhibitor deficiency complicated by a perforated peptic ulcer
topic abdominal imaging
hereditary angioedema
c1 inhibitor deficiency
angioedema
url https://www.termedia.pl/Abdominal-attack-in-a-patient-with-hereditary-angioedema-due-to-C1-inhibitor-deficiency-complicated-by-a-perforated-peptic-ulcer,123,52432,1,1.html
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AT marcinstobiecki abdominalattackinapatientwithhereditaryangioedemaduetoc1inhibitordeficiencycomplicatedbyaperforatedpepticulcer
AT wojciechdyga abdominalattackinapatientwithhereditaryangioedemaduetoc1inhibitordeficiencycomplicatedbyaperforatedpepticulcer
AT tadeuszpopiela abdominalattackinapatientwithhereditaryangioedemaduetoc1inhibitordeficiencycomplicatedbyaperforatedpepticulcer
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