An unusual case of vomiting and arthritis: A diagnostic enigma
Sarcoidosis is a multisystem inflammatory disorder, which can have a myriad of presentations, with atypical presentation not being uncommon. Unless the clinician has a strong suspicion of sarcoidosis, it can be easily missed out. Here, we present an interesting case of a 44-year-old gentleman who ha...
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SAGE Publishing
2022-01-01
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Series: | Indian Journal of Rheumatology |
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Online Access: | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2022;volume=17;issue=1;spage=69;epage=72;aulast=Padiyar |
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author | Shivraj Padiyar Daisy Doley Ramesh Babu John Mathew |
author_facet | Shivraj Padiyar Daisy Doley Ramesh Babu John Mathew |
author_sort | Shivraj Padiyar |
collection | DOAJ |
description | Sarcoidosis is a multisystem inflammatory disorder, which can have a myriad of presentations, with atypical presentation not being uncommon. Unless the clinician has a strong suspicion of sarcoidosis, it can be easily missed out. Here, we present an interesting case of a 44-year-old gentleman who had presented with inflammatory arthritis and vomiting. His serum cortisol levels were low. On further evaluation, he was found to have panhypopituitarism. Magnetic resonance imaging brain showed infiltrative disease involving the pituitary stalk. Imaging of the chest revealed mediastinal nodes which showed nonnecrotizing granulomatous inflammation on histopathology. After ruling out infectious causes a diagnosis of sarcoidosis was made, and the patient had a full recovery with steroids and methotrexate. Sarcoidosis can be a great mimicker presenting with a myriad of complications. Clinicians must be aware of the atypical presentations to diagnose the disease earlier. |
format | Article |
id | doaj-art-db3e093b5a414260bde95efedfd6a189 |
institution | Kabale University |
issn | 0973-3698 0973-3701 |
language | English |
publishDate | 2022-01-01 |
publisher | SAGE Publishing |
record_format | Article |
series | Indian Journal of Rheumatology |
spelling | doaj-art-db3e093b5a414260bde95efedfd6a1892025-02-03T10:23:12ZengSAGE PublishingIndian Journal of Rheumatology0973-36980973-37012022-01-01171697210.4103/injr.injr_359_20An unusual case of vomiting and arthritis: A diagnostic enigmaShivraj PadiyarDaisy DoleyRamesh BabuJohn MathewSarcoidosis is a multisystem inflammatory disorder, which can have a myriad of presentations, with atypical presentation not being uncommon. Unless the clinician has a strong suspicion of sarcoidosis, it can be easily missed out. Here, we present an interesting case of a 44-year-old gentleman who had presented with inflammatory arthritis and vomiting. His serum cortisol levels were low. On further evaluation, he was found to have panhypopituitarism. Magnetic resonance imaging brain showed infiltrative disease involving the pituitary stalk. Imaging of the chest revealed mediastinal nodes which showed nonnecrotizing granulomatous inflammation on histopathology. After ruling out infectious causes a diagnosis of sarcoidosis was made, and the patient had a full recovery with steroids and methotrexate. Sarcoidosis can be a great mimicker presenting with a myriad of complications. Clinicians must be aware of the atypical presentations to diagnose the disease earlier.http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2022;volume=17;issue=1;spage=69;epage=72;aulast=Padiyararthritishypophysitispanhypopituitarismsarcoidosisvomiting |
spellingShingle | Shivraj Padiyar Daisy Doley Ramesh Babu John Mathew An unusual case of vomiting and arthritis: A diagnostic enigma Indian Journal of Rheumatology arthritis hypophysitis panhypopituitarism sarcoidosis vomiting |
title | An unusual case of vomiting and arthritis: A diagnostic enigma |
title_full | An unusual case of vomiting and arthritis: A diagnostic enigma |
title_fullStr | An unusual case of vomiting and arthritis: A diagnostic enigma |
title_full_unstemmed | An unusual case of vomiting and arthritis: A diagnostic enigma |
title_short | An unusual case of vomiting and arthritis: A diagnostic enigma |
title_sort | unusual case of vomiting and arthritis a diagnostic enigma |
topic | arthritis hypophysitis panhypopituitarism sarcoidosis vomiting |
url | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2022;volume=17;issue=1;spage=69;epage=72;aulast=Padiyar |
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