An unusual case of vomiting and arthritis: A diagnostic enigma

Sarcoidosis is a multisystem inflammatory disorder, which can have a myriad of presentations, with atypical presentation not being uncommon. Unless the clinician has a strong suspicion of sarcoidosis, it can be easily missed out. Here, we present an interesting case of a 44-year-old gentleman who ha...

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Main Authors: Shivraj Padiyar, Daisy Doley, Ramesh Babu, John Mathew
Format: Article
Language:English
Published: SAGE Publishing 2022-01-01
Series:Indian Journal of Rheumatology
Subjects:
Online Access:http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2022;volume=17;issue=1;spage=69;epage=72;aulast=Padiyar
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author Shivraj Padiyar
Daisy Doley
Ramesh Babu
John Mathew
author_facet Shivraj Padiyar
Daisy Doley
Ramesh Babu
John Mathew
author_sort Shivraj Padiyar
collection DOAJ
description Sarcoidosis is a multisystem inflammatory disorder, which can have a myriad of presentations, with atypical presentation not being uncommon. Unless the clinician has a strong suspicion of sarcoidosis, it can be easily missed out. Here, we present an interesting case of a 44-year-old gentleman who had presented with inflammatory arthritis and vomiting. His serum cortisol levels were low. On further evaluation, he was found to have panhypopituitarism. Magnetic resonance imaging brain showed infiltrative disease involving the pituitary stalk. Imaging of the chest revealed mediastinal nodes which showed nonnecrotizing granulomatous inflammation on histopathology. After ruling out infectious causes a diagnosis of sarcoidosis was made, and the patient had a full recovery with steroids and methotrexate. Sarcoidosis can be a great mimicker presenting with a myriad of complications. Clinicians must be aware of the atypical presentations to diagnose the disease earlier.
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spelling doaj-art-db3e093b5a414260bde95efedfd6a1892025-02-03T10:23:12ZengSAGE PublishingIndian Journal of Rheumatology0973-36980973-37012022-01-01171697210.4103/injr.injr_359_20An unusual case of vomiting and arthritis: A diagnostic enigmaShivraj PadiyarDaisy DoleyRamesh BabuJohn MathewSarcoidosis is a multisystem inflammatory disorder, which can have a myriad of presentations, with atypical presentation not being uncommon. Unless the clinician has a strong suspicion of sarcoidosis, it can be easily missed out. Here, we present an interesting case of a 44-year-old gentleman who had presented with inflammatory arthritis and vomiting. His serum cortisol levels were low. On further evaluation, he was found to have panhypopituitarism. Magnetic resonance imaging brain showed infiltrative disease involving the pituitary stalk. Imaging of the chest revealed mediastinal nodes which showed nonnecrotizing granulomatous inflammation on histopathology. After ruling out infectious causes a diagnosis of sarcoidosis was made, and the patient had a full recovery with steroids and methotrexate. Sarcoidosis can be a great mimicker presenting with a myriad of complications. Clinicians must be aware of the atypical presentations to diagnose the disease earlier.http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2022;volume=17;issue=1;spage=69;epage=72;aulast=Padiyararthritishypophysitispanhypopituitarismsarcoidosisvomiting
spellingShingle Shivraj Padiyar
Daisy Doley
Ramesh Babu
John Mathew
An unusual case of vomiting and arthritis: A diagnostic enigma
Indian Journal of Rheumatology
arthritis
hypophysitis
panhypopituitarism
sarcoidosis
vomiting
title An unusual case of vomiting and arthritis: A diagnostic enigma
title_full An unusual case of vomiting and arthritis: A diagnostic enigma
title_fullStr An unusual case of vomiting and arthritis: A diagnostic enigma
title_full_unstemmed An unusual case of vomiting and arthritis: A diagnostic enigma
title_short An unusual case of vomiting and arthritis: A diagnostic enigma
title_sort unusual case of vomiting and arthritis a diagnostic enigma
topic arthritis
hypophysitis
panhypopituitarism
sarcoidosis
vomiting
url http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2022;volume=17;issue=1;spage=69;epage=72;aulast=Padiyar
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