Prevention and Treatment of Cytomegalovirus Infection in Transplant Recipients
Over the past decade, significant progress has been made in the understanding of the molecular biology of cytomegalovirus (CMV) and the pathogenesis of CMV infection and disease. The introduction of antiviral agents with efficacy against CMV, coupled with rapid diagnostic techniques in the laborator...
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1993-01-01
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| Series: | Canadian Journal of Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/1993/572607 |
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| _version_ | 1832568390512803840 |
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| author | Jutta K Preiksatis |
| author_facet | Jutta K Preiksatis |
| author_sort | Jutta K Preiksatis |
| collection | DOAJ |
| description | Over the past decade, significant progress has been made in the
understanding of the molecular biology of cytomegalovirus (CMV) and the pathogenesis of CMV infection
and disease. The introduction of antiviral agents with efficacy against CMV, coupled with rapid diagnostic
techniques in the laboratory, have resulted in the design of a number of regimens lo prevent, modify and
treat CMV infections in transplant recipients. Strategies for preventing CMV infection, including donorrecipient
matching, the use of CMV 'safe' cellular blood products, passive and active immunization, and
prophylactic antiviral drugs are discussed. Clinical trials of antiviral drugs alone. or in combination with
immunoglobulin for the treatment of CMV disease are reviewed. |
| format | Article |
| id | doaj-art-db3d10c48c944d9d80ff6555ba6f829f |
| institution | Kabale University |
| issn | 1180-2332 |
| language | English |
| publishDate | 1993-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases |
| spelling | doaj-art-db3d10c48c944d9d80ff6555ba6f829f2025-02-03T00:59:15ZengWileyCanadian Journal of Infectious Diseases1180-23321993-01-014Suppl C435010.1155/1993/572607Prevention and Treatment of Cytomegalovirus Infection in Transplant RecipientsJutta K PreiksatisOver the past decade, significant progress has been made in the understanding of the molecular biology of cytomegalovirus (CMV) and the pathogenesis of CMV infection and disease. The introduction of antiviral agents with efficacy against CMV, coupled with rapid diagnostic techniques in the laboratory, have resulted in the design of a number of regimens lo prevent, modify and treat CMV infections in transplant recipients. Strategies for preventing CMV infection, including donorrecipient matching, the use of CMV 'safe' cellular blood products, passive and active immunization, and prophylactic antiviral drugs are discussed. Clinical trials of antiviral drugs alone. or in combination with immunoglobulin for the treatment of CMV disease are reviewed.http://dx.doi.org/10.1155/1993/572607 |
| spellingShingle | Jutta K Preiksatis Prevention and Treatment of Cytomegalovirus Infection in Transplant Recipients Canadian Journal of Infectious Diseases |
| title | Prevention and Treatment of Cytomegalovirus Infection in Transplant Recipients |
| title_full | Prevention and Treatment of Cytomegalovirus Infection in Transplant Recipients |
| title_fullStr | Prevention and Treatment of Cytomegalovirus Infection in Transplant Recipients |
| title_full_unstemmed | Prevention and Treatment of Cytomegalovirus Infection in Transplant Recipients |
| title_short | Prevention and Treatment of Cytomegalovirus Infection in Transplant Recipients |
| title_sort | prevention and treatment of cytomegalovirus infection in transplant recipients |
| url | http://dx.doi.org/10.1155/1993/572607 |
| work_keys_str_mv | AT juttakpreiksatis preventionandtreatmentofcytomegalovirusinfectionintransplantrecipients |