Potential prognostic value of HER2/CEP17 FISH ratio in HER2-positive non-metastatic breast cancer: a real-world study

Potential prognostic value of HER2/CEP17 FISH ratio in HER2-positive non-metastatic breast cancer: a real-world study

Abstract Background HER2-positive breast cancer (BC) requires anti-HER2 therapy. We aimed to determine whether the expression of the HER2/centromeric probe for chromosome 17 (CEP17) ratio was associated with prognosis in patients with HER2-positive non-metastatic BC. Methods 267 HER2-positive BC wer...

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Bibliographic Details
Main Authors: Fangchao Zheng, Feng Du, Zixuan Yang, Xue Wang, Jian Yue, Yun Ling, Peng Yuan
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
Subjects:
Breast cancer
HER2
HER2/CEP17 ratio
Prognosis
Trastuzumab
Online Access:https://doi.org/10.1007/s12672-025-02495-2
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