Necrotizing Soft Tissue Fasciitis after Intramuscular Injection

Necrotizing soft tissue fasciitis (NSTIs) or necrotizing fasciitis is an infrequent and serious infection. Herein, we describe the clinical course of a female patient who received a diagnosis of NSTIs after gluteus intramuscular injection. We also report the results of our review of published papers...

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Main Authors: Angelica Abbate, Piero Luigi Almasio, Martina Mongitore, Gaetano Di Vita, Rosalia Patti
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Surgery
Online Access:http://dx.doi.org/10.1155/2018/3945497
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author Angelica Abbate
Piero Luigi Almasio
Martina Mongitore
Gaetano Di Vita
Rosalia Patti
author_facet Angelica Abbate
Piero Luigi Almasio
Martina Mongitore
Gaetano Di Vita
Rosalia Patti
author_sort Angelica Abbate
collection DOAJ
description Necrotizing soft tissue fasciitis (NSTIs) or necrotizing fasciitis is an infrequent and serious infection. Herein, we describe the clinical course of a female patient who received a diagnosis of NSTIs after gluteus intramuscular injection. We also report the results of our review of published papers from 1997 to 2017. Since now, 19 cases of NSTIs following intramuscular injections have been described. We focus on the correlation between intramuscular injection and NSTIs onset, especially in immunosuppressed patients treated with corticosteroids, suffering from chronic diseases or drug addicted. Intramuscular injections can provoke severe tissue trauma, representing local portal of infection, even if correctly administrated. Otherwise, it is important not to inject drug in subcutaneous, which is a less vascularized area and therefore more susceptible to infections. Likewise, a proper injecting technique and aspiration prior to injection seem to be valid measure to prevent intra-arterial or para-arterial drug injection with the consequent massive inflammatory reaction. Necrosis at the infection site appears to be independent of the drug, and it is a strong additional risk factor for NSTIs.
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series Case Reports in Surgery
spelling doaj-art-db30675d7e7c43cda7af8ce049bb0bc72025-08-20T02:21:17ZengWileyCase Reports in Surgery2090-69002090-69192018-01-01201810.1155/2018/39454973945497Necrotizing Soft Tissue Fasciitis after Intramuscular InjectionAngelica Abbate0Piero Luigi Almasio1Martina Mongitore2Gaetano Di Vita3Rosalia Patti4General Surgery Unit, Department of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, ItalyBiomedical Department of Internal and Specialistic Medicine, University of Palermo, Palermo, ItalyGeneral Surgery Unit, Department of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, ItalyGeneral Surgery Unit, Department of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, ItalyGeneral Surgery Unit, Department of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, ItalyNecrotizing soft tissue fasciitis (NSTIs) or necrotizing fasciitis is an infrequent and serious infection. Herein, we describe the clinical course of a female patient who received a diagnosis of NSTIs after gluteus intramuscular injection. We also report the results of our review of published papers from 1997 to 2017. Since now, 19 cases of NSTIs following intramuscular injections have been described. We focus on the correlation between intramuscular injection and NSTIs onset, especially in immunosuppressed patients treated with corticosteroids, suffering from chronic diseases or drug addicted. Intramuscular injections can provoke severe tissue trauma, representing local portal of infection, even if correctly administrated. Otherwise, it is important not to inject drug in subcutaneous, which is a less vascularized area and therefore more susceptible to infections. Likewise, a proper injecting technique and aspiration prior to injection seem to be valid measure to prevent intra-arterial or para-arterial drug injection with the consequent massive inflammatory reaction. Necrosis at the infection site appears to be independent of the drug, and it is a strong additional risk factor for NSTIs.http://dx.doi.org/10.1155/2018/3945497
spellingShingle Angelica Abbate
Piero Luigi Almasio
Martina Mongitore
Gaetano Di Vita
Rosalia Patti
Necrotizing Soft Tissue Fasciitis after Intramuscular Injection
Case Reports in Surgery
title Necrotizing Soft Tissue Fasciitis after Intramuscular Injection
title_full Necrotizing Soft Tissue Fasciitis after Intramuscular Injection
title_fullStr Necrotizing Soft Tissue Fasciitis after Intramuscular Injection
title_full_unstemmed Necrotizing Soft Tissue Fasciitis after Intramuscular Injection
title_short Necrotizing Soft Tissue Fasciitis after Intramuscular Injection
title_sort necrotizing soft tissue fasciitis after intramuscular injection
url http://dx.doi.org/10.1155/2018/3945497
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AT martinamongitore necrotizingsofttissuefasciitisafterintramuscularinjection
AT gaetanodivita necrotizingsofttissuefasciitisafterintramuscularinjection
AT rosaliapatti necrotizingsofttissuefasciitisafterintramuscularinjection