AMP-activated protein kinase suppresses the in vitro and in vivo proliferation of hepatocellular carcinoma.

AMP-activated protein kinase suppresses the in vitro and in vivo proliferation of hepatocellular carcinoma.

AMP-activated protein kinase (AMPK) is a central metabolic sensor and plays an important role in regulating glucose, lipid and cholesterol metabolism. Therefore, AMPK is a key therapeutic target in diabetes. Recent pilot studies have suggested that diabetes drugs may reduce the risk of cancer by aff...

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Main Authors: Jidong Cheng, Tianliang Huang, Youfeng Li, Yubai Guo, Yuzhang Zhu, Qingjia Wang, Xiaojun Tan, Weisheng Chen, Yongneng Zhang, Weijie Cheng, Tetsuya Yamamoto, Xubin Jing, Jiexiong Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0093256&type=printable
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