Characterization of two neutralizing monoclonal antibodies with conformational epitopes against porcine deltacoronavirus

Characterization of two neutralizing monoclonal antibodies with conformational epitopes against porcine deltacoronavirus

Abstract Porcine deltacoronavirus (PDCoV) is a globally distributed swine enteropathogenic virus that emerged in the last decade. A recent report of PDCoV infection in Haitian children also highlights potential public health implications. In this study, two monoclonal antibodies (mAbs), 1C2 and 5H5,...

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Bibliographic Details
Main Authors: Wan Lu, Hongtao Cao, Yongle Yang, Yangyang Sun, Dong Yang, Priscilla F. Gerber, Xiangdong Li, Yaowei Huang, Bin Wang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Animal Diseases
Subjects:
Porcine deltacoronavirus (PDCoV)
Spike
Neutralizing antibody
Monoclonal antibody
Epitope
Online Access:https://doi.org/10.1186/s44149-025-00156-z
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