Advancements in single-cell techniques for examining the HIV reservoir: pathways to a cure

Advancements in single-cell techniques for examining the HIV reservoir: pathways to a cure

ABSTRACT Human immunodeficiency virus (HIV) is largely incurable, due to the presence of a viral reservoir, which primarily consists of resting CD4+ T cells and other long-lived cells like macrophages. These reservoir cells, which persist despite suppressive antiretroviral therapy (ART), are thought...

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Bibliographic Details
Main Authors: Nokuzola Mbhele, Benjamin Chimukangara, Lynn Tyers, Frank Maldarelli, Andrew D. Redd
Format: Article
Language:English
Published: American Society for Microbiology 2025-07-01
Series:mBio
Subjects:
HIV-1
HIV-1 reservoir
single-cell
HIV cure
Online Access:https://journals.asm.org/doi/10.1128/mbio.00655-25
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