Efficacy of cefoperazone-sulbactam as a component of combination therapy for carbapenem-resistant Acinetobacter baumannii bloodstream infection in intensive care units: a multicenter retrospective propensity score-matched study

Efficacy of cefoperazone-sulbactam as a component of combination therapy for carbapenem-resistant Acinetobacter baumannii bloodstream infection in intensive care units: a multicenter retrospective propensity score-matched study

Abstract Background In this study, we aimed to evaluate the efficacy of cefoperazone-sulbactam-containing (CSC) combination therapy for carbapenem-resistant Acinetobacter baumannii (CRAB) bloodstream infections (BSI) patients in intensive care unit (ICU). Methods This multicenter, retrospective coho...

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Main Authors: Sheng-Huei Wang, Yu-Chao Lin, Ming-Cheng Chan, Kuang-Yao Yang, Chau-Chyun Sheu, Biing-Ru Wu, Wei-Hsuan Huang, Jia-Yih Feng, Chia-Min Chen, Zi-Xeng Weng, Chung-Kan Peng, Shih-En Tang, and the T-CARE (Taiwan Critical Care and Infection) Group
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Infectious Diseases
Subjects:
Carbapenem-resistant Acinetobacter baumannii
Cefoperazone-sulbactam
Bloodstream infection
Clinical failure
Mortality
Online Access:https://doi.org/10.1186/s12879-025-11205-w
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