Risk factors for long-term severe tricuspid regurgitation following mitral valve replacement: a retrospective study
Abstract Background The aim of this study is to identify factors associated with the development of long-term severe tricuspid regurgitation (TR) following mitral valve replacement (MVR). Methods A retrospective analysis was conducted involving 308 patients who underwent single-valve MVR at Xuzhou C...
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2025-01-01
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| Online Access: | https://doi.org/10.1186/s12872-024-04459-w |
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| author | Shan-Shan Li Ling-Zhi Dou Bing Han Bing-Rong Miao Sen Wang He Jiang Yu-Li Zheng Jian-Ming Li Hong-Yun Ruan |
| author_facet | Shan-Shan Li Ling-Zhi Dou Bing Han Bing-Rong Miao Sen Wang He Jiang Yu-Li Zheng Jian-Ming Li Hong-Yun Ruan |
| author_sort | Shan-Shan Li |
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| description | Abstract Background The aim of this study is to identify factors associated with the development of long-term severe tricuspid regurgitation (TR) following mitral valve replacement (MVR). Methods A retrospective analysis was conducted involving 308 patients who underwent single-valve MVR at Xuzhou Central Hospital between April 2017 and December 2022. Preoperative color Doppler ultrasound indicated that all patients had either no or mild to moderate tricuspid regurgitation. Postoperative follow-up was carried out over several years, and patients were categorized into two groups based on the severity of TR: 258 patients with non-severe TR (observation group) and 50 patients with severe TR (control group). Clinical data, medical history, the performance of tricuspid valvuloplasty during surgery, and echocardiographic parameters before and after the procedure were recorded. Comparative analysis between the two groups was performed, and logistic regression analysis was used to identify factors associated with the long-term development of severe TR post-MVR. Results Logistic regression analysis indicated that serum creatinine levels (OR = 1.023, P = 0.026), atrial fibrillation (OR = 2.780, P = 0.040), and a history of permanent pacemaker implantation (OR = 3.029, P = 0.039) were significantly associated with the development of severe TR over time. In contrast, concurrent intraoperative tricuspid valvuloplasty was associated with a reduced risk of TR (OR = 0.315, P = 0.002). Conclusions Elevated serum creatinine, atrial fibrillation, and a history of permanent pacemaker implantation were positively associated with the long-term occurrence of severe TR following MVR. In contrast, concurrent intraoperative tricuspid valvuloplasty was found to reduce the likelihood of severe TR development. |
| format | Article |
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| institution | Kabale University |
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| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
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| series | BMC Cardiovascular Disorders |
| spelling | doaj-art-daef5ef9d1e04e76a20e043bae46b5042025-01-19T12:09:27ZengBMCBMC Cardiovascular Disorders1471-22612025-01-012511710.1186/s12872-024-04459-wRisk factors for long-term severe tricuspid regurgitation following mitral valve replacement: a retrospective studyShan-Shan Li0Ling-Zhi Dou1Bing Han2Bing-Rong Miao3Sen Wang4He Jiang5Yu-Li Zheng6Jian-Ming Li7Hong-Yun Ruan8Department of Cardiology, Xuzhou Central HospitalDepartment of Cardiology, Xuzhou Central HospitalDepartment of Cardiology, Xuzhou Central HospitalDepartment of Cardiac Surgery, Xuzhou Central HospitalDepartment of Cardiology, Xuzhou Central HospitalDepartment of Cardiology, Xuzhou Central HospitalDepartment of Cardiology, Xuzhou Central HospitalDepartment of Cardiac Surgery, Xuzhou Central HospitalDepartment of Cardiology, Xuzhou Central HospitalAbstract Background The aim of this study is to identify factors associated with the development of long-term severe tricuspid regurgitation (TR) following mitral valve replacement (MVR). Methods A retrospective analysis was conducted involving 308 patients who underwent single-valve MVR at Xuzhou Central Hospital between April 2017 and December 2022. Preoperative color Doppler ultrasound indicated that all patients had either no or mild to moderate tricuspid regurgitation. Postoperative follow-up was carried out over several years, and patients were categorized into two groups based on the severity of TR: 258 patients with non-severe TR (observation group) and 50 patients with severe TR (control group). Clinical data, medical history, the performance of tricuspid valvuloplasty during surgery, and echocardiographic parameters before and after the procedure were recorded. Comparative analysis between the two groups was performed, and logistic regression analysis was used to identify factors associated with the long-term development of severe TR post-MVR. Results Logistic regression analysis indicated that serum creatinine levels (OR = 1.023, P = 0.026), atrial fibrillation (OR = 2.780, P = 0.040), and a history of permanent pacemaker implantation (OR = 3.029, P = 0.039) were significantly associated with the development of severe TR over time. In contrast, concurrent intraoperative tricuspid valvuloplasty was associated with a reduced risk of TR (OR = 0.315, P = 0.002). Conclusions Elevated serum creatinine, atrial fibrillation, and a history of permanent pacemaker implantation were positively associated with the long-term occurrence of severe TR following MVR. In contrast, concurrent intraoperative tricuspid valvuloplasty was found to reduce the likelihood of severe TR development.https://doi.org/10.1186/s12872-024-04459-wAtrial fibrillationColor DopplerMitral valve replacementPermanent pacemaker implantationRegression analysisTricuspid regurgitation |
| spellingShingle | Shan-Shan Li Ling-Zhi Dou Bing Han Bing-Rong Miao Sen Wang He Jiang Yu-Li Zheng Jian-Ming Li Hong-Yun Ruan Risk factors for long-term severe tricuspid regurgitation following mitral valve replacement: a retrospective study BMC Cardiovascular Disorders Atrial fibrillation Color Doppler Mitral valve replacement Permanent pacemaker implantation Regression analysis Tricuspid regurgitation |
| title | Risk factors for long-term severe tricuspid regurgitation following mitral valve replacement: a retrospective study |
| title_full | Risk factors for long-term severe tricuspid regurgitation following mitral valve replacement: a retrospective study |
| title_fullStr | Risk factors for long-term severe tricuspid regurgitation following mitral valve replacement: a retrospective study |
| title_full_unstemmed | Risk factors for long-term severe tricuspid regurgitation following mitral valve replacement: a retrospective study |
| title_short | Risk factors for long-term severe tricuspid regurgitation following mitral valve replacement: a retrospective study |
| title_sort | risk factors for long term severe tricuspid regurgitation following mitral valve replacement a retrospective study |
| topic | Atrial fibrillation Color Doppler Mitral valve replacement Permanent pacemaker implantation Regression analysis Tricuspid regurgitation |
| url | https://doi.org/10.1186/s12872-024-04459-w |
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