Assessment of COVID-19 Vaccine Impact on Women’s Menstrual Health within an 18-Month Follow-Up

Considering menstruation as a crucial factor in females’ health and fertility, any factor that could change its cycle is important. This study was conducted from April 2021 to October 2022 on females who got 3 doses of vaccines against SARS-CoV-2 through different platforms. The participants were re...

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Main Authors: Mona Sadat Larijani, Sana Eybpoosh, Delaram Doroud, Anahita Bavand, Ladan Moradi, Fatemeh Ashrafian, Parinaz Tajmehrabi Namini, Mahsan Zali, Amitis Ramezani
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Obstetrics and Gynecology International
Online Access:http://dx.doi.org/10.1155/2024/7344506
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author Mona Sadat Larijani
Sana Eybpoosh
Delaram Doroud
Anahita Bavand
Ladan Moradi
Fatemeh Ashrafian
Parinaz Tajmehrabi Namini
Mahsan Zali
Amitis Ramezani
author_facet Mona Sadat Larijani
Sana Eybpoosh
Delaram Doroud
Anahita Bavand
Ladan Moradi
Fatemeh Ashrafian
Parinaz Tajmehrabi Namini
Mahsan Zali
Amitis Ramezani
author_sort Mona Sadat Larijani
collection DOAJ
description Considering menstruation as a crucial factor in females’ health and fertility, any factor that could change its cycle is important. This study was conducted from April 2021 to October 2022 on females who got 3 doses of vaccines against SARS-CoV-2 through different platforms. The participants were requested to provide the trained experts with any changes regarding menstrual cycles after each dose of the vaccine up to 6 months after the booster shots. The disturbances related to the vaccines were identified by the adverse events committee to find possible associations with the applied vaccines. Of 308 women who participated until the end of the study, 22 (7.1%) complained about at least one abnormality in their menstrual patterns. The most common disturbance was metrorrhagia as 10 (48%) incidences followed by menorrhagia as 6 events (24.2%). Notably, the identified complaints were persistent in 59% of the patients. In addition, 14 studied cases developed COVID-19 infection after menstrual disorders. In these cases, COVID-19 could also play a role in the persistence of postvaccine menstrual disturbances. COVID-19 vaccination could affect menstrual cycle in women with no remarkable previous medical history. More longitudinal studies are required regarding this issue.
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spelling doaj-art-dad08955550d4b469abb7caf3102ad0d2025-02-02T23:08:54ZengWileyObstetrics and Gynecology International1687-95972024-01-01202410.1155/2024/7344506Assessment of COVID-19 Vaccine Impact on Women’s Menstrual Health within an 18-Month Follow-UpMona Sadat Larijani0Sana Eybpoosh1Delaram Doroud2Anahita Bavand3Ladan Moradi4Fatemeh Ashrafian5Parinaz Tajmehrabi Namini6Mahsan Zali7Amitis Ramezani8Clinical Research DepartmentDepartment of Epidemiology and BiostatisticsQuality Control DepartmentClinical Research DepartmentClinical Research DepartmentClinical Research DepartmentClinical Research DepartmentClinical Research DepartmentClinical Research DepartmentConsidering menstruation as a crucial factor in females’ health and fertility, any factor that could change its cycle is important. This study was conducted from April 2021 to October 2022 on females who got 3 doses of vaccines against SARS-CoV-2 through different platforms. The participants were requested to provide the trained experts with any changes regarding menstrual cycles after each dose of the vaccine up to 6 months after the booster shots. The disturbances related to the vaccines were identified by the adverse events committee to find possible associations with the applied vaccines. Of 308 women who participated until the end of the study, 22 (7.1%) complained about at least one abnormality in their menstrual patterns. The most common disturbance was metrorrhagia as 10 (48%) incidences followed by menorrhagia as 6 events (24.2%). Notably, the identified complaints were persistent in 59% of the patients. In addition, 14 studied cases developed COVID-19 infection after menstrual disorders. In these cases, COVID-19 could also play a role in the persistence of postvaccine menstrual disturbances. COVID-19 vaccination could affect menstrual cycle in women with no remarkable previous medical history. More longitudinal studies are required regarding this issue.http://dx.doi.org/10.1155/2024/7344506
spellingShingle Mona Sadat Larijani
Sana Eybpoosh
Delaram Doroud
Anahita Bavand
Ladan Moradi
Fatemeh Ashrafian
Parinaz Tajmehrabi Namini
Mahsan Zali
Amitis Ramezani
Assessment of COVID-19 Vaccine Impact on Women’s Menstrual Health within an 18-Month Follow-Up
Obstetrics and Gynecology International
title Assessment of COVID-19 Vaccine Impact on Women’s Menstrual Health within an 18-Month Follow-Up
title_full Assessment of COVID-19 Vaccine Impact on Women’s Menstrual Health within an 18-Month Follow-Up
title_fullStr Assessment of COVID-19 Vaccine Impact on Women’s Menstrual Health within an 18-Month Follow-Up
title_full_unstemmed Assessment of COVID-19 Vaccine Impact on Women’s Menstrual Health within an 18-Month Follow-Up
title_short Assessment of COVID-19 Vaccine Impact on Women’s Menstrual Health within an 18-Month Follow-Up
title_sort assessment of covid 19 vaccine impact on women s menstrual health within an 18 month follow up
url http://dx.doi.org/10.1155/2024/7344506
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