Diagnosis of Turner syndrome after presenting with ischemic cardiomyopathy: A case report
Untreated Turner syndrome increases the risk of ischemic cardiomyopathy. We report a 44-year-old Chinese woman who was diagnosed with Turner syndrome owing to symptoms of ischemic cardiomyopathy and heart failure confirmed through cardiac magnetic resonance imaging, coronary angiography, and abnorma...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2025-02-01
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| Series: | SAGE Open Medical Case Reports |
| Online Access: | https://doi.org/10.1177/2050313X251318519 |
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| author | Hui Zheng Liting Guo Yanwei Wei Yunqiang Zhang Yanfang Guan |
| author_facet | Hui Zheng Liting Guo Yanwei Wei Yunqiang Zhang Yanfang Guan |
| author_sort | Hui Zheng |
| collection | DOAJ |
| description | Untreated Turner syndrome increases the risk of ischemic cardiomyopathy. We report a 44-year-old Chinese woman who was diagnosed with Turner syndrome owing to symptoms of ischemic cardiomyopathy and heart failure confirmed through cardiac magnetic resonance imaging, coronary angiography, and abnormal brain natriuretic peptide levels. The patient had a short stature, underdeveloped uterus with primary amenorrhea, and congenital left upper pulmonary vein reflux to the right atrium; she was diagnosed with Turner syndrome through karyotype analysis. Because she refused coronary artery bypass grafting, she received aspirin, torasemide, atorvastatin, bisoprolol, sacubitril/valsartan, empagliflozin, spironolactone, and complex packing estradiol tablets/estradiol and dydrogesterone tablets (1–10 mg). After 3 months of treatment, her heart failure symptoms disappeared. Ischemic heart disease is a high-risk complication in patients with Turner syndrome. Prompt diagnosis and comprehensive management through a multidisciplinary approach can improve patient outcomes. Further evidence is needed to establish a secondary prevention strategy for Turner syndrome with ischemic cardiomyopathy. |
| format | Article |
| id | doaj-art-dace15855b934af89327eb66c8d0867d |
| institution | Kabale University |
| issn | 2050-313X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | SAGE Open Medical Case Reports |
| spelling | doaj-art-dace15855b934af89327eb66c8d0867d2025-02-03T10:03:56ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2025-02-011310.1177/2050313X251318519Diagnosis of Turner syndrome after presenting with ischemic cardiomyopathy: A case reportHui Zheng0Liting Guo1Yanwei Wei2Yunqiang Zhang3Yanfang Guan4Department of Endocrinology, TEDA International Cardiovascular Hospital, Tianjin University, Tianjin, ChinaDepartment of Endocrinology, TEDA International Cardiovascular Hospital, Tianjin, ChinaDepartment of Heart Failure, TEDA International Cardiovascular Hospital, Tianjin, ChinaDepartment of Heart Failure, TEDA International Cardiovascular Hospital, Tianjin, ChinaDepartment of Radiology, TEDA International Cardiovascular Hospital, Tianjin, ChinaUntreated Turner syndrome increases the risk of ischemic cardiomyopathy. We report a 44-year-old Chinese woman who was diagnosed with Turner syndrome owing to symptoms of ischemic cardiomyopathy and heart failure confirmed through cardiac magnetic resonance imaging, coronary angiography, and abnormal brain natriuretic peptide levels. The patient had a short stature, underdeveloped uterus with primary amenorrhea, and congenital left upper pulmonary vein reflux to the right atrium; she was diagnosed with Turner syndrome through karyotype analysis. Because she refused coronary artery bypass grafting, she received aspirin, torasemide, atorvastatin, bisoprolol, sacubitril/valsartan, empagliflozin, spironolactone, and complex packing estradiol tablets/estradiol and dydrogesterone tablets (1–10 mg). After 3 months of treatment, her heart failure symptoms disappeared. Ischemic heart disease is a high-risk complication in patients with Turner syndrome. Prompt diagnosis and comprehensive management through a multidisciplinary approach can improve patient outcomes. Further evidence is needed to establish a secondary prevention strategy for Turner syndrome with ischemic cardiomyopathy.https://doi.org/10.1177/2050313X251318519 |
| spellingShingle | Hui Zheng Liting Guo Yanwei Wei Yunqiang Zhang Yanfang Guan Diagnosis of Turner syndrome after presenting with ischemic cardiomyopathy: A case report SAGE Open Medical Case Reports |
| title | Diagnosis of Turner syndrome after presenting with ischemic cardiomyopathy: A case report |
| title_full | Diagnosis of Turner syndrome after presenting with ischemic cardiomyopathy: A case report |
| title_fullStr | Diagnosis of Turner syndrome after presenting with ischemic cardiomyopathy: A case report |
| title_full_unstemmed | Diagnosis of Turner syndrome after presenting with ischemic cardiomyopathy: A case report |
| title_short | Diagnosis of Turner syndrome after presenting with ischemic cardiomyopathy: A case report |
| title_sort | diagnosis of turner syndrome after presenting with ischemic cardiomyopathy a case report |
| url | https://doi.org/10.1177/2050313X251318519 |
| work_keys_str_mv | AT huizheng diagnosisofturnersyndromeafterpresentingwithischemiccardiomyopathyacasereport AT litingguo diagnosisofturnersyndromeafterpresentingwithischemiccardiomyopathyacasereport AT yanweiwei diagnosisofturnersyndromeafterpresentingwithischemiccardiomyopathyacasereport AT yunqiangzhang diagnosisofturnersyndromeafterpresentingwithischemiccardiomyopathyacasereport AT yanfangguan diagnosisofturnersyndromeafterpresentingwithischemiccardiomyopathyacasereport |