Human Hepatocytes and Differentiated Adult-Derived Human Liver Stem/Progenitor Cells Display In Vitro Immunosuppressive Properties Mediated, at Least in Part, through the Nonclassical HLA Class I Molecule HLA-G

Human Hepatocytes and Differentiated Adult-Derived Human Liver Stem/Progenitor Cells Display In Vitro Immunosuppressive Properties Mediated, at Least in Part, through the Nonclassical HLA Class I Molecule HLA-G

One of the main challenges in liver cell therapy (LCT) is the induction of a tolerogenic microenvironment to promote graft acceptance in the recipient. Little is known about the immunomodulatory potential of the hepatic cells used in liver cell therapy. In this work, we wanted to evaluate the immuno...

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Bibliographic Details
Main Authors: Catherine A. Lombard, Gwenaëlle Sana, Joël LeMaoult, Mehdi Najar, Joachim Ravau, Floriane André, Fatima Bouhtit, Marina Daouya, Maria Loustau, Mustapha Najimi, Laurence Lagneaux, Edgardo D. Carosella, Etienne M. Sokal
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2019/8250584
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