Risk of medication-induced lactic acidosis and hyperlactatemia: a pharmacovigilance study of the United States Food and Drug Administration’s Adverse Event Reporting System database

Risk of medication-induced lactic acidosis and hyperlactatemia: a pharmacovigilance study of the United States Food and Drug Administration’s Adverse Event Reporting System database

ObjectiveLactic acidosis and hyperlactatemia (LAHL) are predictors of poor clinical outcomes in critically ill patients. This research aimed to specify medications reported in association with LAHL, thus providing valuable insights into medication safety.MethodsSpontaneous reports were excavated fro...

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Bibliographic Details
Main Authors: Houci Yang, Haibin Dai, Xveying Chen, Jiaqi Huang, Fangzhou Miao, Jiani Lv, Jiali Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
lactic acidosis
hyperlactatemia
pharmacovigilance
FAERS
adverse reaction
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1555955/full
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