Melanotic Neuroectodermal Tumor of Infancy in the Maxilla
Melanotic neuroectodermal tumors of infancy (MNTIs) are rare fast-growing tumors with high recurrence rates. These tumors, which originate in the neural crest, commonly occur in the anterior maxilla of children under the age of one. Here, we describe an MNTI case in a two-month-old girl with increas...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2013/726815 |
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| author | Daniel Falbo Martins de Souza Daniel Isaac Sendyk Juliana Seo Eduardo Vasques da Fonseca Maria da Graça Naclério-Homem Maria Cristina Zindel Deboni |
| author_facet | Daniel Falbo Martins de Souza Daniel Isaac Sendyk Juliana Seo Eduardo Vasques da Fonseca Maria da Graça Naclério-Homem Maria Cristina Zindel Deboni |
| author_sort | Daniel Falbo Martins de Souza |
| collection | DOAJ |
| description | Melanotic neuroectodermal tumors of infancy (MNTIs) are rare fast-growing tumors with high recurrence rates. These tumors, which originate in the neural crest, commonly occur in the anterior maxilla of children under the age of one. Here, we describe an MNTI case in a two-month-old girl with increasing swelling in the left cheek. MNTI was diagnosed in this case following tomography and biopsy. The patient's histological and immunohistochemical profile indicated a remarkable combination of neural, melanocytic, and epithelial cell differentiation. One year following tumor excision, a follow-up examination revealed that the child exhibited no tumor recurrence. Approximately 260 cases of MNTI have been reported since this type of tumor was first described. In the present case, early diagnosis minimized the difficulties and risks associated with treatment and facilitated an optimal outcome. Despite complete surgical excision, careful followup is recommended. In addition, maxillary functional orthopedics and reconstruction may be necessary in cases of MNTI. |
| format | Article |
| id | doaj-art-dab1a6a7af8842038af0fa808211b66f |
| institution | Kabale University |
| issn | 2090-6447 2090-6455 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dentistry |
| spelling | doaj-art-dab1a6a7af8842038af0fa808211b66f2025-02-03T06:05:47ZengWileyCase Reports in Dentistry2090-64472090-64552013-01-01201310.1155/2013/726815726815Melanotic Neuroectodermal Tumor of Infancy in the MaxillaDaniel Falbo Martins de Souza0Daniel Isaac Sendyk1Juliana Seo2Eduardo Vasques da Fonseca3Maria da Graça Naclério-Homem4Maria Cristina Zindel Deboni5Department of Oral Surgery, School of Dentistry, University of São Paulo, Avenida Prof. Lineu Prestes 2227, Butantã, 05508-000 São Paulo, SP, BrazilDepartment of Oral Surgery, School of Dentistry, University of São Paulo, Avenida Prof. Lineu Prestes 2227, Butantã, 05508-000 São Paulo, SP, BrazilDepartment of Oral Pathology, School of Dentistry, University of São Paulo, São Paulo, SP, BrazilDepartment of Oral and Maxillofacial Surgery, Conjunto Hospitalar do Mandaqui, São Paulo, SP, BrazilDepartment of Oral Surgery, School of Dentistry, University of São Paulo, Avenida Prof. Lineu Prestes 2227, Butantã, 05508-000 São Paulo, SP, BrazilDepartment of Oral Surgery, School of Dentistry, University of São Paulo, Avenida Prof. Lineu Prestes 2227, Butantã, 05508-000 São Paulo, SP, BrazilMelanotic neuroectodermal tumors of infancy (MNTIs) are rare fast-growing tumors with high recurrence rates. These tumors, which originate in the neural crest, commonly occur in the anterior maxilla of children under the age of one. Here, we describe an MNTI case in a two-month-old girl with increasing swelling in the left cheek. MNTI was diagnosed in this case following tomography and biopsy. The patient's histological and immunohistochemical profile indicated a remarkable combination of neural, melanocytic, and epithelial cell differentiation. One year following tumor excision, a follow-up examination revealed that the child exhibited no tumor recurrence. Approximately 260 cases of MNTI have been reported since this type of tumor was first described. In the present case, early diagnosis minimized the difficulties and risks associated with treatment and facilitated an optimal outcome. Despite complete surgical excision, careful followup is recommended. In addition, maxillary functional orthopedics and reconstruction may be necessary in cases of MNTI.http://dx.doi.org/10.1155/2013/726815 |
| spellingShingle | Daniel Falbo Martins de Souza Daniel Isaac Sendyk Juliana Seo Eduardo Vasques da Fonseca Maria da Graça Naclério-Homem Maria Cristina Zindel Deboni Melanotic Neuroectodermal Tumor of Infancy in the Maxilla Case Reports in Dentistry |
| title | Melanotic Neuroectodermal Tumor of Infancy in the Maxilla |
| title_full | Melanotic Neuroectodermal Tumor of Infancy in the Maxilla |
| title_fullStr | Melanotic Neuroectodermal Tumor of Infancy in the Maxilla |
| title_full_unstemmed | Melanotic Neuroectodermal Tumor of Infancy in the Maxilla |
| title_short | Melanotic Neuroectodermal Tumor of Infancy in the Maxilla |
| title_sort | melanotic neuroectodermal tumor of infancy in the maxilla |
| url | http://dx.doi.org/10.1155/2013/726815 |
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