A Case of Systemic Lupus Erythematosus Presenting as Guillain-Barré Syndrome

Systemic lupus erythematosus (SLE) is an autoimmune systemic disease with multiple organ involvement with high morbidity and mortality rate. Among the severe potential fatal complications are those of the central and peripheral nervous system which usually develop during the course of the disease an...

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Main Authors: Helen Chioma Okoh, Sandeep Singh Lubana, Spencer Langevin, Susan Sanelli-Russo, Adriana Abrudescu
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2015/528026
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author Helen Chioma Okoh
Sandeep Singh Lubana
Spencer Langevin
Susan Sanelli-Russo
Adriana Abrudescu
author_facet Helen Chioma Okoh
Sandeep Singh Lubana
Spencer Langevin
Susan Sanelli-Russo
Adriana Abrudescu
author_sort Helen Chioma Okoh
collection DOAJ
description Systemic lupus erythematosus (SLE) is an autoimmune systemic disease with multiple organ involvement with high morbidity and mortality rate. Among the severe potential fatal complications are those of the central and peripheral nervous system which usually develop during the course of the disease and very rarely from the outset of the disease. We are reporting a rare case of Miller-Fisher (MFS) variant of Guillain-Barré syndrome (GBS) as the first manifestation of SLE in a 41-year-old female who progressed to flaccid paralysis with no neurological improvement with initial immunosuppressive therapy, plasmapheresis, and first cycle of intravenous immunoglobulin (IVIG) but with remarkable and complete recovery after the second 5-day course of IVIG.
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institution Kabale University
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spelling doaj-art-daa898af04384c48bc32eb0eca673bb02025-02-03T05:53:42ZengWileyCase Reports in Rheumatology2090-68892090-68972015-01-01201510.1155/2015/528026528026A Case of Systemic Lupus Erythematosus Presenting as Guillain-Barré SyndromeHelen Chioma Okoh0Sandeep Singh Lubana1Spencer Langevin2Susan Sanelli-Russo3Adriana Abrudescu4Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, NY 11432, USAIcahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, NY 11432, USAIcahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, NY 11432, USAIcahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, NY 11432, USAIcahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, NY 11432, USASystemic lupus erythematosus (SLE) is an autoimmune systemic disease with multiple organ involvement with high morbidity and mortality rate. Among the severe potential fatal complications are those of the central and peripheral nervous system which usually develop during the course of the disease and very rarely from the outset of the disease. We are reporting a rare case of Miller-Fisher (MFS) variant of Guillain-Barré syndrome (GBS) as the first manifestation of SLE in a 41-year-old female who progressed to flaccid paralysis with no neurological improvement with initial immunosuppressive therapy, plasmapheresis, and first cycle of intravenous immunoglobulin (IVIG) but with remarkable and complete recovery after the second 5-day course of IVIG.http://dx.doi.org/10.1155/2015/528026
spellingShingle Helen Chioma Okoh
Sandeep Singh Lubana
Spencer Langevin
Susan Sanelli-Russo
Adriana Abrudescu
A Case of Systemic Lupus Erythematosus Presenting as Guillain-Barré Syndrome
Case Reports in Rheumatology
title A Case of Systemic Lupus Erythematosus Presenting as Guillain-Barré Syndrome
title_full A Case of Systemic Lupus Erythematosus Presenting as Guillain-Barré Syndrome
title_fullStr A Case of Systemic Lupus Erythematosus Presenting as Guillain-Barré Syndrome
title_full_unstemmed A Case of Systemic Lupus Erythematosus Presenting as Guillain-Barré Syndrome
title_short A Case of Systemic Lupus Erythematosus Presenting as Guillain-Barré Syndrome
title_sort case of systemic lupus erythematosus presenting as guillain barre syndrome
url http://dx.doi.org/10.1155/2015/528026
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