Combination of machine learning and Raman spectroscopy for prediction of drug release in targeted drug delivery formulations

Combination of machine learning and Raman spectroscopy for prediction of drug release in targeted drug delivery formulations

Abstract In this research, advanced regression techniques are investigated for modeling intricate release patterns utilizing a high-dimensional dataset comprising more than 1500 spectrum-based variables and categorical inputs. The spectral data are collected from Raman spectroscopy for analysis of d...

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Bibliographic Details
Main Authors: Wael A. Mahdi, Adel Alhowyan, Ahmad J. Obaidullah
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Drug release
Kernel ridge regression
Kernel-based extreme learning machine
Quantile regression
Colonic drug delivery
Online Access:https://doi.org/10.1038/s41598-025-10417-z
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