Psychiatric and Behavioral Complications of GPi DBS in an Adolescent with Myoclonus Dystonia

Myoclonus dystonia is a rare movement disorder that often causes significant disability. Deep brain stimulation of the internal pallidum (GPi DBS) is a recommended treatment for those who do not respond to pharmacotherapy or who have intolerable side effects. This paper reports on the case of a 17-y...

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Main Authors: Graciela Kriegel, Melanie I. Stuckey
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2019/1947962
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author Graciela Kriegel
Melanie I. Stuckey
author_facet Graciela Kriegel
Melanie I. Stuckey
author_sort Graciela Kriegel
collection DOAJ
description Myoclonus dystonia is a rare movement disorder that often causes significant disability. Deep brain stimulation of the internal pallidum (GPi DBS) is a recommended treatment for those who do not respond to pharmacotherapy or who have intolerable side effects. This paper reports on the case of a 17-year-old male who was admitted to a tertiary level mental healthcare facility for treatment of psychiatric and behavioral symptoms thought to be related to GPi DBS. Prior to GPi DBS insertion, the patient was diagnosed with anxiety and mild obsessive compulsive disorder (OCD). Following insertion, his OCD became severe and he developed depression, Tourette syndrome, and stuttering. His first admission to a psychiatric unit was for management of a manic episode following treatment for depression with fluoxetine, and he began to exhibit severe aggressive behavior. GPi DBS was turned off, but there were neither changes in dystonic movements nor improvement in aggressive behavior or psychiatric symptoms, though stuttering improved. The patient was transferred to a secure treatment centre where he was able to gain control over his behaviors with intense dialectical behavior therapy, but the aggressive behavior and safety concerns continue to persist today.
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spelling doaj-art-da564a3270fc4a8f86a331e540e3df5a2025-02-03T06:13:08ZengWileyCase Reports in Psychiatry2090-682X2090-68382019-01-01201910.1155/2019/19479621947962Psychiatric and Behavioral Complications of GPi DBS in an Adolescent with Myoclonus DystoniaGraciela Kriegel0Melanie I. Stuckey1Ontario Shores Centre for Mental Health Sciences, Whitby, CanadaOntario Shores Centre for Mental Health Sciences, Whitby, CanadaMyoclonus dystonia is a rare movement disorder that often causes significant disability. Deep brain stimulation of the internal pallidum (GPi DBS) is a recommended treatment for those who do not respond to pharmacotherapy or who have intolerable side effects. This paper reports on the case of a 17-year-old male who was admitted to a tertiary level mental healthcare facility for treatment of psychiatric and behavioral symptoms thought to be related to GPi DBS. Prior to GPi DBS insertion, the patient was diagnosed with anxiety and mild obsessive compulsive disorder (OCD). Following insertion, his OCD became severe and he developed depression, Tourette syndrome, and stuttering. His first admission to a psychiatric unit was for management of a manic episode following treatment for depression with fluoxetine, and he began to exhibit severe aggressive behavior. GPi DBS was turned off, but there were neither changes in dystonic movements nor improvement in aggressive behavior or psychiatric symptoms, though stuttering improved. The patient was transferred to a secure treatment centre where he was able to gain control over his behaviors with intense dialectical behavior therapy, but the aggressive behavior and safety concerns continue to persist today.http://dx.doi.org/10.1155/2019/1947962
spellingShingle Graciela Kriegel
Melanie I. Stuckey
Psychiatric and Behavioral Complications of GPi DBS in an Adolescent with Myoclonus Dystonia
Case Reports in Psychiatry
title Psychiatric and Behavioral Complications of GPi DBS in an Adolescent with Myoclonus Dystonia
title_full Psychiatric and Behavioral Complications of GPi DBS in an Adolescent with Myoclonus Dystonia
title_fullStr Psychiatric and Behavioral Complications of GPi DBS in an Adolescent with Myoclonus Dystonia
title_full_unstemmed Psychiatric and Behavioral Complications of GPi DBS in an Adolescent with Myoclonus Dystonia
title_short Psychiatric and Behavioral Complications of GPi DBS in an Adolescent with Myoclonus Dystonia
title_sort psychiatric and behavioral complications of gpi dbs in an adolescent with myoclonus dystonia
url http://dx.doi.org/10.1155/2019/1947962
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