Food allergens and oral immunotherapy as indicators of eosinophilic oesophagitis

Eosinophilic esophagitis (EoE) is a chronic immune-mediated esophageal disease, clinically characterised by symptoms of esophageal dysfunction and histologically by eosinophilic infiltration of its wall. The last 3 decades have seen a sharp increase in its incidence to the point that it is called th...

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Main Authors: Andrzej Kuźmiński, Justyna Przybyszewska, Zbigniew Bartuzi
Format: Article
Language:English
Published: Termedia Publishing House 2024-05-01
Series:Gastroenterology Review
Subjects:
Online Access:https://www.termedia.pl/Food-allergens-and-oral-immunotherapy-as-indicators-r-nof-eosinophilic-oesophagitis,41,54110,1,1.html
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author Andrzej Kuźmiński
Justyna Przybyszewska
Zbigniew Bartuzi
author_facet Andrzej Kuźmiński
Justyna Przybyszewska
Zbigniew Bartuzi
author_sort Andrzej Kuźmiński
collection DOAJ
description Eosinophilic esophagitis (EoE) is a chronic immune-mediated esophageal disease, clinically characterised by symptoms of esophageal dysfunction and histologically by eosinophilic infiltration of its wall. The last 3 decades have seen a sharp increase in its incidence to the point that it is called the second most common esophageal disease after reflux disease in some recent studies. The main indicators of EoE are food allergens and in recent years the extremely important role of oral immunotherapy (OIT) in the development of this disease has also been increasingly raised. To date, the appearance of EoE in the course of OIT is an absolute indication for discontinuation of this procedure; however, other therapeutic options that do not require termination of this procedure are increasingly being advocated. Unfortunately, our knowledge of EoE is full of gaps and requires numerous studies to fill in the missing elements of the pathogenesis and clinic of the described disease.
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publishDate 2024-05-01
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series Gastroenterology Review
spelling doaj-art-da256af1556a490981461c61977e8e5d2025-01-27T11:31:36ZengTermedia Publishing HouseGastroenterology Review1895-57701897-43172024-05-0119436236710.5114/pg.2024.13953454110Food allergens and oral immunotherapy as indicators of eosinophilic oesophagitisAndrzej KuźmińskiJustyna PrzybyszewskaZbigniew BartuziEosinophilic esophagitis (EoE) is a chronic immune-mediated esophageal disease, clinically characterised by symptoms of esophageal dysfunction and histologically by eosinophilic infiltration of its wall. The last 3 decades have seen a sharp increase in its incidence to the point that it is called the second most common esophageal disease after reflux disease in some recent studies. The main indicators of EoE are food allergens and in recent years the extremely important role of oral immunotherapy (OIT) in the development of this disease has also been increasingly raised. To date, the appearance of EoE in the course of OIT is an absolute indication for discontinuation of this procedure; however, other therapeutic options that do not require termination of this procedure are increasingly being advocated. Unfortunately, our knowledge of EoE is full of gaps and requires numerous studies to fill in the missing elements of the pathogenesis and clinic of the described disease.https://www.termedia.pl/Food-allergens-and-oral-immunotherapy-as-indicators-r-nof-eosinophilic-oesophagitis,41,54110,1,1.htmleosinophilic oesophagitis allergy gastrointestinal tract.
spellingShingle Andrzej Kuźmiński
Justyna Przybyszewska
Zbigniew Bartuzi
Food allergens and oral immunotherapy as indicators of eosinophilic oesophagitis
Gastroenterology Review
eosinophilic oesophagitis
allergy
gastrointestinal tract.
title Food allergens and oral immunotherapy as indicators of eosinophilic oesophagitis
title_full Food allergens and oral immunotherapy as indicators of eosinophilic oesophagitis
title_fullStr Food allergens and oral immunotherapy as indicators of eosinophilic oesophagitis
title_full_unstemmed Food allergens and oral immunotherapy as indicators of eosinophilic oesophagitis
title_short Food allergens and oral immunotherapy as indicators of eosinophilic oesophagitis
title_sort food allergens and oral immunotherapy as indicators of eosinophilic oesophagitis
topic eosinophilic oesophagitis
allergy
gastrointestinal tract.
url https://www.termedia.pl/Food-allergens-and-oral-immunotherapy-as-indicators-r-nof-eosinophilic-oesophagitis,41,54110,1,1.html
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