<i>Syntrichia laevipila</i> Brid., a Bryophyta from Northwest Argentina as a Source of Antioxidants and Antimicrobials
In recent years, numerous studies have emerged on the biological activities of bryophytes and their potential for therapeutic use. However, mosses appear to be a relatively overlooked group. The objective of this study was to conduct a phytochemical analysis of one hydroalcoholic extract of <i>...
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2025-01-01
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| author | Luis Ignacio Jiménez Florencia Maria Correa Uriburu José Javier Martínez Chamás Guillermo Martin Suárez Iris Catiana Zampini Mario J. Simirgiotis María Inés Isla |
| author_facet | Luis Ignacio Jiménez Florencia Maria Correa Uriburu José Javier Martínez Chamás Guillermo Martin Suárez Iris Catiana Zampini Mario J. Simirgiotis María Inés Isla |
| author_sort | Luis Ignacio Jiménez |
| collection | DOAJ |
| description | In recent years, numerous studies have emerged on the biological activities of bryophytes and their potential for therapeutic use. However, mosses appear to be a relatively overlooked group. The objective of this study was to conduct a phytochemical analysis of one hydroalcoholic extract of <i>Syntrichia laevipila</i> and to evaluate its potential as an antioxidant and antimicrobial agent. The moss was collected in the Chaco Serrano region of Argentina, specifically on <i>Jacaranda mimosifolia</i>, and subsequently extracted by maceration in ethanol/water. UHPLC/ESI/MS/MS analysis identified 32 peaks, including phenolic compounds (phenolic acids, lignans, chalcones, and flavonoids) and non-hydrophilic compounds (terpenoids, fatty acids, and brassinosteroids). Maslinic and oleanolic acids, two triterpenoids present in S. <i>laevipila,</i> were also detected in <i>J. mimosifolia</i>, a substrate of this moss. The concentration of phenolic compounds was 19.05 ± 0.21 µg GAE/mL, while the total flavonoid concentration was 13.13 ± 0.33 µg QE/mL. The determination of reducing and total sugars yielded 0.22 ± 0.03 mg GE/mL and 1.26 ± 0.24 mg GE/mL, respectively, while the concentration of soluble proteins was 90.60 ± 4.50 µg BSAE/mL. The extract exhibited antioxidant properties by scavenging ABTS<sup>•+</sup>, H<sub>2</sub>O<sub>2</sub>, AAPH, and HO<sup>•</sup> radicals. Additionally, it demonstrated antibacterial activity by inhibiting the growth of four strains of <i>Staphylococcus aureus</i>. The data obtained suggest that the hydroalcoholic extract of <i>S. laevipila</i> possesses significant potential as a natural antioxidant and antimicrobial agent, making it a promising candidate for the development of phytotherapeutic and cosmetic products. |
| format | Article |
| id | doaj-art-da1f10a5afcb43d6a530166de4531164 |
| institution | Kabale University |
| issn | 2223-7747 |
| language | English |
| publishDate | 2025-01-01 |
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| series | Plants |
| spelling | doaj-art-da1f10a5afcb43d6a530166de45311642025-01-24T13:46:57ZengMDPI AGPlants2223-77472025-01-0114225310.3390/plants14020253<i>Syntrichia laevipila</i> Brid., a Bryophyta from Northwest Argentina as a Source of Antioxidants and AntimicrobialsLuis Ignacio Jiménez0Florencia Maria Correa Uriburu1José Javier Martínez Chamás2Guillermo Martin Suárez3Iris Catiana Zampini4Mario J. Simirgiotis5María Inés Isla6Instituto de Bioprospección y Fisiología Vegetal (INBIOFIV-CONICET-UNT), San Miguel de Tucumán T4000CBG, ArgentinaInstituto de Bioprospección y Fisiología Vegetal (INBIOFIV-CONICET-UNT), San Miguel de Tucumán T4000CBG, ArgentinaInstituto de Bioprospección y Fisiología Vegetal (INBIOFIV-CONICET-UNT), San Miguel de Tucumán T4000CBG, ArgentinaFacultad de Ciencias Naturales e IML, Universidad Nacional de Tucumán (UNT), San Miguel de Tucumán T4000JFE, ArgentinaInstituto de Bioprospección y Fisiología Vegetal (INBIOFIV-CONICET-UNT), San Miguel de Tucumán T4000CBG, ArgentinaInstituto de Farmacia, Facultad de Ciencias, Campus Isla Teja, Universidad Austral de Chile, Valdivia 5090000, ChileInstituto de Bioprospección y Fisiología Vegetal (INBIOFIV-CONICET-UNT), San Miguel de Tucumán T4000CBG, ArgentinaIn recent years, numerous studies have emerged on the biological activities of bryophytes and their potential for therapeutic use. However, mosses appear to be a relatively overlooked group. The objective of this study was to conduct a phytochemical analysis of one hydroalcoholic extract of <i>Syntrichia laevipila</i> and to evaluate its potential as an antioxidant and antimicrobial agent. The moss was collected in the Chaco Serrano region of Argentina, specifically on <i>Jacaranda mimosifolia</i>, and subsequently extracted by maceration in ethanol/water. UHPLC/ESI/MS/MS analysis identified 32 peaks, including phenolic compounds (phenolic acids, lignans, chalcones, and flavonoids) and non-hydrophilic compounds (terpenoids, fatty acids, and brassinosteroids). Maslinic and oleanolic acids, two triterpenoids present in S. <i>laevipila,</i> were also detected in <i>J. mimosifolia</i>, a substrate of this moss. The concentration of phenolic compounds was 19.05 ± 0.21 µg GAE/mL, while the total flavonoid concentration was 13.13 ± 0.33 µg QE/mL. The determination of reducing and total sugars yielded 0.22 ± 0.03 mg GE/mL and 1.26 ± 0.24 mg GE/mL, respectively, while the concentration of soluble proteins was 90.60 ± 4.50 µg BSAE/mL. The extract exhibited antioxidant properties by scavenging ABTS<sup>•+</sup>, H<sub>2</sub>O<sub>2</sub>, AAPH, and HO<sup>•</sup> radicals. Additionally, it demonstrated antibacterial activity by inhibiting the growth of four strains of <i>Staphylococcus aureus</i>. The data obtained suggest that the hydroalcoholic extract of <i>S. laevipila</i> possesses significant potential as a natural antioxidant and antimicrobial agent, making it a promising candidate for the development of phytotherapeutic and cosmetic products.https://www.mdpi.com/2223-7747/14/2/253bryophytesantioxidant capacityantimicrobial activityphytochemical screeningmoss-derived bioactives |
| spellingShingle | Luis Ignacio Jiménez Florencia Maria Correa Uriburu José Javier Martínez Chamás Guillermo Martin Suárez Iris Catiana Zampini Mario J. Simirgiotis María Inés Isla <i>Syntrichia laevipila</i> Brid., a Bryophyta from Northwest Argentina as a Source of Antioxidants and Antimicrobials Plants bryophytes antioxidant capacity antimicrobial activity phytochemical screening moss-derived bioactives |
| title | <i>Syntrichia laevipila</i> Brid., a Bryophyta from Northwest Argentina as a Source of Antioxidants and Antimicrobials |
| title_full | <i>Syntrichia laevipila</i> Brid., a Bryophyta from Northwest Argentina as a Source of Antioxidants and Antimicrobials |
| title_fullStr | <i>Syntrichia laevipila</i> Brid., a Bryophyta from Northwest Argentina as a Source of Antioxidants and Antimicrobials |
| title_full_unstemmed | <i>Syntrichia laevipila</i> Brid., a Bryophyta from Northwest Argentina as a Source of Antioxidants and Antimicrobials |
| title_short | <i>Syntrichia laevipila</i> Brid., a Bryophyta from Northwest Argentina as a Source of Antioxidants and Antimicrobials |
| title_sort | i syntrichia laevipila i brid a bryophyta from northwest argentina as a source of antioxidants and antimicrobials |
| topic | bryophytes antioxidant capacity antimicrobial activity phytochemical screening moss-derived bioactives |
| url | https://www.mdpi.com/2223-7747/14/2/253 |
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