Disseminated Tuberculosis Mimicking Ankylosing Spondylitis

Ankylosing spondylitis is a chronic inflammatory disorder affecting mainly the axial skeleton. Here we report a case of a man with a clinical suspicion of ankylosing spondylitis but with a persistence of increased inflammatory markers. In this case, 18F-FDG-PET/CT revealed multiple hypermetabolic le...

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Bibliographic Details
Main Authors: Valérie Huyge, Serge Goldman, Muhammad S. Soyfoo
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2011/195085
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Summary:Ankylosing spondylitis is a chronic inflammatory disorder affecting mainly the axial skeleton. Here we report a case of a man with a clinical suspicion of ankylosing spondylitis but with a persistence of increased inflammatory markers. In this case, 18F-FDG-PET/CT revealed multiple hypermetabolic lesions in axial skeleton, lymph nodes, and the lung, suggestive of either disseminated tuberculosis or lymphoma. Histological analysis of the pulmonary lesion revealed mycobacterium tuberculosis. This case highlights, firstly, the importance of excluding other diagnoses in the presence of clinical picture of ankylosing spondylitis and high inflammatory markers and, secondly, the determining role of PET/CT.
ISSN:2090-6889
2090-6897