Adherence to Antihypertensive Medications in Iranian Patients

Introduction. Appropriate adherence to medication is still a challenging issue for hypertensive patients. We determined adherence to antihypertensive(s) and its associated factors among 280 Iranian patients. Methods. They were recruited consecutively from private and university health centers and ph...

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Main Authors: Azin Behnood-Rod, Omid Rabbanifar, Pirouz Pourzargar, Alireza Rai, Zahra Saadat, Habibollah Saadat, Yashar Moharamzad, Donald E. Morisky
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.1155/2016/1508752
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author Azin Behnood-Rod
Omid Rabbanifar
Pirouz Pourzargar
Alireza Rai
Zahra Saadat
Habibollah Saadat
Yashar Moharamzad
Donald E. Morisky
author_facet Azin Behnood-Rod
Omid Rabbanifar
Pirouz Pourzargar
Alireza Rai
Zahra Saadat
Habibollah Saadat
Yashar Moharamzad
Donald E. Morisky
author_sort Azin Behnood-Rod
collection DOAJ
description Introduction. Appropriate adherence to medication is still a challenging issue for hypertensive patients. We determined adherence to antihypertensive(s) and its associated factors among 280 Iranian patients. Methods. They were recruited consecutively from private and university health centers and pharmacies in four cities. The validated Persian version of the 8-item Morisky Medication Adherence Scale (MMAS-8) was administered to measure adherence. Results. Mean (±SD) overall MMAS-8 score was 5.75 (±1.88). About half of the sample (139 cases, 49.6%) showed low adherence (MMAS-8 score < 6). There was a negative linear association between the MMAS-8 score and systolic BP (r=-0.231, P<0.001) as well as diastolic BP (r=-0.280, P<0.001). In linear regression model, overweight/obesity (B=-0.52, P=0.02), previous history of admission to emergency services due to hypertensive crisis (B=-0.79, P=0.001), and getting medication directly from drugstore without refill prescription in hand (B=-0.51, P=0.04) were factors recognized to have statistically significant association with the MMAS-8 score. Conclusion. Antihypertensive adherence was unsatisfactory. We suggest that health care providers pay special attention and make use of the aforementioned findings in their routine visits of hypertensive patients to recognize those who are vulnerable to poor adherence.
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spelling doaj-art-da10938ecedd48f7be25378f872072e62025-02-03T01:26:27ZengWileyInternational Journal of Hypertension2090-03842090-03922016-01-01201610.1155/2016/15087521508752Adherence to Antihypertensive Medications in Iranian PatientsAzin Behnood-Rod0Omid Rabbanifar1Pirouz Pourzargar2Alireza Rai3Zahra Saadat4Habibollah Saadat5Yashar Moharamzad6Donald E. Morisky7Islamic Azad University, Tehran Medical Branch, Tehran, IranZanjan University of Medical Sciences, Zanjan, IranCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IranSchool of Medicine, Kermanshah University of Medical Sciences, Kermanshah, IranCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IranCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IranCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Community Health Sciences, UCLA Fielding School of Public Health, Los Angeles, CA, USAIntroduction. Appropriate adherence to medication is still a challenging issue for hypertensive patients. We determined adherence to antihypertensive(s) and its associated factors among 280 Iranian patients. Methods. They were recruited consecutively from private and university health centers and pharmacies in four cities. The validated Persian version of the 8-item Morisky Medication Adherence Scale (MMAS-8) was administered to measure adherence. Results. Mean (±SD) overall MMAS-8 score was 5.75 (±1.88). About half of the sample (139 cases, 49.6%) showed low adherence (MMAS-8 score < 6). There was a negative linear association between the MMAS-8 score and systolic BP (r=-0.231, P<0.001) as well as diastolic BP (r=-0.280, P<0.001). In linear regression model, overweight/obesity (B=-0.52, P=0.02), previous history of admission to emergency services due to hypertensive crisis (B=-0.79, P=0.001), and getting medication directly from drugstore without refill prescription in hand (B=-0.51, P=0.04) were factors recognized to have statistically significant association with the MMAS-8 score. Conclusion. Antihypertensive adherence was unsatisfactory. We suggest that health care providers pay special attention and make use of the aforementioned findings in their routine visits of hypertensive patients to recognize those who are vulnerable to poor adherence.http://dx.doi.org/10.1155/2016/1508752
spellingShingle Azin Behnood-Rod
Omid Rabbanifar
Pirouz Pourzargar
Alireza Rai
Zahra Saadat
Habibollah Saadat
Yashar Moharamzad
Donald E. Morisky
Adherence to Antihypertensive Medications in Iranian Patients
International Journal of Hypertension
title Adherence to Antihypertensive Medications in Iranian Patients
title_full Adherence to Antihypertensive Medications in Iranian Patients
title_fullStr Adherence to Antihypertensive Medications in Iranian Patients
title_full_unstemmed Adherence to Antihypertensive Medications in Iranian Patients
title_short Adherence to Antihypertensive Medications in Iranian Patients
title_sort adherence to antihypertensive medications in iranian patients
url http://dx.doi.org/10.1155/2016/1508752
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