Transposons and Integrons: Natural Genetic Engineering of Bacterial Resistance
The advent of antibiotics in clinical medicine has resulted in the emergence of multiresistant strains of bacteria. Bacteria possess sophisticated mechanisms of genetic exchange that have driven their recent evolution. Among these are transposons and integrons, the latter having interesting parallel...
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| Format: | Article |
| Language: | English |
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Wiley
1999-01-01
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| Series: | Canadian Journal of Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/1999/619276 |
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| _version_ | 1832554864835559424 |
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| author | Paul H Roy |
| author_facet | Paul H Roy |
| author_sort | Paul H Roy |
| collection | DOAJ |
| description | The advent of antibiotics in clinical medicine has resulted in the
emergence of multiresistant strains of bacteria. Bacteria possess
sophisticated mechanisms of genetic exchange that have driven
their recent evolution. Among these are transposons and integrons,
the latter having interesting parallels with genetic engineering
techniques used in the laboratory. An understanding of these
mechanisms through studies of the molecular basis of the
dissemination of resistance genes will aid rational choices in
antibiotic therapy. |
| format | Article |
| id | doaj-art-da01a15f3ecb4bdeb7fe21a1ac924fed |
| institution | Kabale University |
| issn | 1180-2332 |
| language | English |
| publishDate | 1999-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases |
| spelling | doaj-art-da01a15f3ecb4bdeb7fe21a1ac924fed2025-02-03T05:50:25ZengWileyCanadian Journal of Infectious Diseases1180-23321999-01-0110Suppl C5C8C10.1155/1999/619276Transposons and Integrons: Natural Genetic Engineering of Bacterial ResistancePaul H Roy0Centre de Recherche en Infectiologie and Département de Biochimie (Faculté des Sciences et de Génie), Université Laval, Ste-Foy, Québec, CanadaThe advent of antibiotics in clinical medicine has resulted in the emergence of multiresistant strains of bacteria. Bacteria possess sophisticated mechanisms of genetic exchange that have driven their recent evolution. Among these are transposons and integrons, the latter having interesting parallels with genetic engineering techniques used in the laboratory. An understanding of these mechanisms through studies of the molecular basis of the dissemination of resistance genes will aid rational choices in antibiotic therapy.http://dx.doi.org/10.1155/1999/619276 |
| spellingShingle | Paul H Roy Transposons and Integrons: Natural Genetic Engineering of Bacterial Resistance Canadian Journal of Infectious Diseases |
| title | Transposons and Integrons: Natural Genetic Engineering of Bacterial Resistance |
| title_full | Transposons and Integrons: Natural Genetic Engineering of Bacterial Resistance |
| title_fullStr | Transposons and Integrons: Natural Genetic Engineering of Bacterial Resistance |
| title_full_unstemmed | Transposons and Integrons: Natural Genetic Engineering of Bacterial Resistance |
| title_short | Transposons and Integrons: Natural Genetic Engineering of Bacterial Resistance |
| title_sort | transposons and integrons natural genetic engineering of bacterial resistance |
| url | http://dx.doi.org/10.1155/1999/619276 |
| work_keys_str_mv | AT paulhroy transposonsandintegronsnaturalgeneticengineeringofbacterialresistance |