Increased Risk of Atrial and Ventricular Arrhythmia in Long-Lasting Psoriasis Patients
Background. Several reports have demonstrated an association between psoriasis and cardiovascular diseases. P wave dispersion (PWD) is the most important electrocardiographic (ECG) markers used to evaluate the risk of atrial arrhythmias. QT dispersion (QTD) can be used to assess homogeneity of card...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2013/901215 |
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| author | Hakki Simsek Musa Sahin Aytac Akyol Serkan Akdag Hatice Uce Ozkol Hasan Ali Gumrukcuoglu Yilmaz Gunes |
| author_facet | Hakki Simsek Musa Sahin Aytac Akyol Serkan Akdag Hatice Uce Ozkol Hasan Ali Gumrukcuoglu Yilmaz Gunes |
| author_sort | Hakki Simsek |
| collection | DOAJ |
| description | Background. Several reports have demonstrated an association between psoriasis and cardiovascular diseases. P wave dispersion (PWD) is the most important electrocardiographic (ECG) markers used to evaluate the risk of atrial arrhythmias. QT dispersion (QTD) can be used to assess homogeneity of cardiac repolarization and may be a risk for ventricular arrhythmias. Aim. To search PWD and QTD in patients with psoriasis. Methods. Ninety-four outpatient psoriasis patients and 51 healthy people were evaluated by physical examination, 12-lead ECG, and transthoracic echocardiography. Severity of the psoriasis was evaluated by psoriasis area and severity index (PASI). Results. Mean disease duration was 129.4±83.9 (range, 3–360) months and PASI ranged from 0 to 34.0 (mean ± SD; 7.6±6.7). Compared to control group, psoriatic patients had significantly shorter Pmax and Pmin durations, longer QTcmax, and greater PWD and QTcD. Transmitral deceleration time (DT) and isovolumetric relaxation time (IVRT) were significantly longer among psoriasis patients. QTcD and PWD were significantly correlated with disease duration (r=0.693, P<0.001, and r=0.368, P=0.003, resp.). Conclusions. In this study, we found that both PWD and QTcD are increased in psoriasis patients compared to healthy subjects. In addition, they had longer DT and IVRT. |
| format | Article |
| id | doaj-art-d9f10dc86f4e4b6d8c87eaa5e30b3e7a |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-d9f10dc86f4e4b6d8c87eaa5e30b3e7a2025-02-03T01:25:32ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/901215901215Increased Risk of Atrial and Ventricular Arrhythmia in Long-Lasting Psoriasis PatientsHakki Simsek0Musa Sahin1Aytac Akyol2Serkan Akdag3Hatice Uce Ozkol4Hasan Ali Gumrukcuoglu5Yilmaz Gunes6Cardiology Department, Faculty of Medicine, Yuzunci Yil University, 65200 Van, TurkeyCardiology Department, Faculty of Medicine, Yuzunci Yil University, 65200 Van, TurkeyVan High Edücation and Research Hospital, 65100 Van, TurkeyVan High Edücation and Research Hospital, 65100 Van, TurkeyDermatology Department, Faculty of Medicine, Yuzunci Yil University, 65200 Van, TurkeyCardiology Department, Faculty of Medicine, Yuzunci Yil University, 65200 Van, TurkeyCardiology Department, Hisar Intercontinental Hospital, 34768 Istanbul, TurkeyBackground. Several reports have demonstrated an association between psoriasis and cardiovascular diseases. P wave dispersion (PWD) is the most important electrocardiographic (ECG) markers used to evaluate the risk of atrial arrhythmias. QT dispersion (QTD) can be used to assess homogeneity of cardiac repolarization and may be a risk for ventricular arrhythmias. Aim. To search PWD and QTD in patients with psoriasis. Methods. Ninety-four outpatient psoriasis patients and 51 healthy people were evaluated by physical examination, 12-lead ECG, and transthoracic echocardiography. Severity of the psoriasis was evaluated by psoriasis area and severity index (PASI). Results. Mean disease duration was 129.4±83.9 (range, 3–360) months and PASI ranged from 0 to 34.0 (mean ± SD; 7.6±6.7). Compared to control group, psoriatic patients had significantly shorter Pmax and Pmin durations, longer QTcmax, and greater PWD and QTcD. Transmitral deceleration time (DT) and isovolumetric relaxation time (IVRT) were significantly longer among psoriasis patients. QTcD and PWD were significantly correlated with disease duration (r=0.693, P<0.001, and r=0.368, P=0.003, resp.). Conclusions. In this study, we found that both PWD and QTcD are increased in psoriasis patients compared to healthy subjects. In addition, they had longer DT and IVRT.http://dx.doi.org/10.1155/2013/901215 |
| spellingShingle | Hakki Simsek Musa Sahin Aytac Akyol Serkan Akdag Hatice Uce Ozkol Hasan Ali Gumrukcuoglu Yilmaz Gunes Increased Risk of Atrial and Ventricular Arrhythmia in Long-Lasting Psoriasis Patients The Scientific World Journal |
| title | Increased Risk of Atrial and Ventricular Arrhythmia in Long-Lasting Psoriasis Patients |
| title_full | Increased Risk of Atrial and Ventricular Arrhythmia in Long-Lasting Psoriasis Patients |
| title_fullStr | Increased Risk of Atrial and Ventricular Arrhythmia in Long-Lasting Psoriasis Patients |
| title_full_unstemmed | Increased Risk of Atrial and Ventricular Arrhythmia in Long-Lasting Psoriasis Patients |
| title_short | Increased Risk of Atrial and Ventricular Arrhythmia in Long-Lasting Psoriasis Patients |
| title_sort | increased risk of atrial and ventricular arrhythmia in long lasting psoriasis patients |
| url | http://dx.doi.org/10.1155/2013/901215 |
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