Adiponectin in Cardiovascular Inflammation and Obesity
Inflammation is widely known to play a key role in the development and progression of cardiovascular diseases. It is becoming increasingly evident that obesity is linked to many proinflammatory and obesity...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
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| Series: | International Journal of Inflammation |
| Online Access: | http://dx.doi.org/10.4061/2011/376909 |
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| _version_ | 1832567900944203776 |
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| author | Tamar R. Aprahamian Flora Sam |
| author_facet | Tamar R. Aprahamian Flora Sam |
| author_sort | Tamar R. Aprahamian |
| collection | DOAJ |
| description | Inflammation is
widely known to play a key role in the
development and progression of cardiovascular
diseases. It is becoming increasingly evident
that obesity is linked to many proinflammatory
and obesity-associated cardiovascular conditions
(e.g., metabolic syndrome, acute coronary
syndrome, and congestive heart failure). It has
been observed that adipokines play an
increasingly large role in systemic and local
inflammation. Therefore, adipose tissue may have
a more important role than previously thought in
the pathogenesis of several disease types. This
review explores the recently described role of
adiponectin as an immunomodulatory factor and
how it intersects with the inflammation
associated with both cardiovascular and
autoimmune pathologies. |
| format | Article |
| id | doaj-art-d9e31ae4451e4e329d0797a3721fdb5e |
| institution | Kabale University |
| issn | 2042-0099 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Inflammation |
| spelling | doaj-art-d9e31ae4451e4e329d0797a3721fdb5e2025-02-03T01:00:21ZengWileyInternational Journal of Inflammation2042-00992011-01-01201110.4061/2011/376909376909Adiponectin in Cardiovascular Inflammation and ObesityTamar R. Aprahamian0Flora Sam1Renal Section, Evans Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USACardiovascular Section, Evans Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USAInflammation is widely known to play a key role in the development and progression of cardiovascular diseases. It is becoming increasingly evident that obesity is linked to many proinflammatory and obesity-associated cardiovascular conditions (e.g., metabolic syndrome, acute coronary syndrome, and congestive heart failure). It has been observed that adipokines play an increasingly large role in systemic and local inflammation. Therefore, adipose tissue may have a more important role than previously thought in the pathogenesis of several disease types. This review explores the recently described role of adiponectin as an immunomodulatory factor and how it intersects with the inflammation associated with both cardiovascular and autoimmune pathologies.http://dx.doi.org/10.4061/2011/376909 |
| spellingShingle | Tamar R. Aprahamian Flora Sam Adiponectin in Cardiovascular Inflammation and Obesity International Journal of Inflammation |
| title | Adiponectin in Cardiovascular Inflammation and Obesity |
| title_full | Adiponectin in Cardiovascular Inflammation and Obesity |
| title_fullStr | Adiponectin in Cardiovascular Inflammation and Obesity |
| title_full_unstemmed | Adiponectin in Cardiovascular Inflammation and Obesity |
| title_short | Adiponectin in Cardiovascular Inflammation and Obesity |
| title_sort | adiponectin in cardiovascular inflammation and obesity |
| url | http://dx.doi.org/10.4061/2011/376909 |
| work_keys_str_mv | AT tamarraprahamian adiponectinincardiovascularinflammationandobesity AT florasam adiponectinincardiovascularinflammationandobesity |