Integrating protein language models and automatic biofoundry for enhanced protein evolution
Abstract Traditional protein engineering methods, such as directed evolution, while effective, are often slow and labor-intensive. Advances in machine learning and automated biofoundry present new opportunities for optimizing these processes. This study devises a protein language model-enabled autom...
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| Main Authors: | Qiang Zhang, Wanyi Chen, Ming Qin, Yuhao Wang, Zhongji Pu, Keyan Ding, Yuyue Liu, Qunfeng Zhang, Dongfang Li, Xinjia Li, Yu Zhao, Jianhua Yao, Lei Huang, Jianping Wu, Lirong Yang, Huajun Chen, Haoran Yu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-56751-8 |
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