Expectant Management of Miscarriage in View of NICE Guideline 154

Objective. To find out the success rate of conservative management of complete two weeks for miscarriage in view of NICE Guideline 154. Design. Prospective observational study. Setting. Early pregnancy assessment units of District General Hospital in the United Kingdom. Participants. Women of less t...

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Main Authors: Junaid Rafi, Haroona Khalil
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Pregnancy
Online Access:http://dx.doi.org/10.1155/2014/824527
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author Junaid Rafi
Haroona Khalil
author_facet Junaid Rafi
Haroona Khalil
author_sort Junaid Rafi
collection DOAJ
description Objective. To find out the success rate of conservative management of complete two weeks for miscarriage in view of NICE Guideline 154. Design. Prospective observational study. Setting. Early pregnancy assessment units of District General Hospital in the United Kingdom. Participants. Women of less than 14 weeks’ gestation, with a diagnosis of miscarriage (missed miscarriage/anembryonic or incomplete miscarriage). Interventions. Expectant management for two weeks. Main Outcome Measure. (1) Efficacy of 2-week expectant management, that is, complete resolution of miscarriage based either on self-reporting of patient after passing products of conception at home between D0 and D14 of expectant management or confirmation on scan at D14, and (2) short-term complications needing strong analgesia, blood transfusion, and antibiotics. Results. Expectant management of miscarriage for 2 weeks from the day of diagnosis was successful in 58% (64 /111) and failed in 42% (47/111). Conclusions. Expectant management success rate is consistent with the results from the longitudinal studies and RCTs published in the past. It is a safe option as none of the patients on expectant/medical management needed strong analgesia/antibiotics or blood transfusion.
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spelling doaj-art-d9b32bca491a4ce1b284a3cc9bebc1ed2025-02-03T01:31:28ZengWileyJournal of Pregnancy2090-27272090-27352014-01-01201410.1155/2014/824527824527Expectant Management of Miscarriage in View of NICE Guideline 154Junaid Rafi0Haroona Khalil1Ipswich Hospital NHS Trust Hospital, Heath Road Ipswich, IP4 5PD, UKIpswich Hospital NHS Trust Hospital, Heath Road Ipswich, IP4 5PD, UKObjective. To find out the success rate of conservative management of complete two weeks for miscarriage in view of NICE Guideline 154. Design. Prospective observational study. Setting. Early pregnancy assessment units of District General Hospital in the United Kingdom. Participants. Women of less than 14 weeks’ gestation, with a diagnosis of miscarriage (missed miscarriage/anembryonic or incomplete miscarriage). Interventions. Expectant management for two weeks. Main Outcome Measure. (1) Efficacy of 2-week expectant management, that is, complete resolution of miscarriage based either on self-reporting of patient after passing products of conception at home between D0 and D14 of expectant management or confirmation on scan at D14, and (2) short-term complications needing strong analgesia, blood transfusion, and antibiotics. Results. Expectant management of miscarriage for 2 weeks from the day of diagnosis was successful in 58% (64 /111) and failed in 42% (47/111). Conclusions. Expectant management success rate is consistent with the results from the longitudinal studies and RCTs published in the past. It is a safe option as none of the patients on expectant/medical management needed strong analgesia/antibiotics or blood transfusion.http://dx.doi.org/10.1155/2014/824527
spellingShingle Junaid Rafi
Haroona Khalil
Expectant Management of Miscarriage in View of NICE Guideline 154
Journal of Pregnancy
title Expectant Management of Miscarriage in View of NICE Guideline 154
title_full Expectant Management of Miscarriage in View of NICE Guideline 154
title_fullStr Expectant Management of Miscarriage in View of NICE Guideline 154
title_full_unstemmed Expectant Management of Miscarriage in View of NICE Guideline 154
title_short Expectant Management of Miscarriage in View of NICE Guideline 154
title_sort expectant management of miscarriage in view of nice guideline 154
url http://dx.doi.org/10.1155/2014/824527
work_keys_str_mv AT junaidrafi expectantmanagementofmiscarriageinviewofniceguideline154
AT haroonakhalil expectantmanagementofmiscarriageinviewofniceguideline154