Hypoxic-ischemic encefalopathy: Clinical course and prognosis
Background. Establishing the value of neurological examination, and additional diagnostic methods (ultrasonography and magnetic resonance imaging of the brain) in the diagnosis and prognosis of hypoxic-ischemic encephalopathy and its treatment, tracking the clinical course, and making the prognosis...
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2003-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2003/0042-84500303291C.pdf |
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| author | Ćosić-Cerovac Nataša Todorović Slobodanka M. Jović Nebojša J. Prostran Milica Š. |
| author_facet | Ćosić-Cerovac Nataša Todorović Slobodanka M. Jović Nebojša J. Prostran Milica Š. |
| author_sort | Ćosić-Cerovac Nataša |
| collection | DOAJ |
| description | Background. Establishing the value of neurological examination, and additional diagnostic methods (ultrasonography and magnetic resonance imaging of the brain) in the diagnosis and prognosis of hypoxic-ischemic encephalopathy and its treatment, tracking the clinical course, and making the prognosis of neurological development in newborn infants with hypoxic-ischemic encefalopathy. Methods. The group of 40 term newborn infants with suspected intrauterine asphyxia was examined. All the infants were prospectivelly followed untill the 3rd year of age at the Clinic for Neurology and Psychiatry for Children and Youth in order to estimate their neurological development and to diagnose the occurence of persistent neurological disorders. All the infants were analyzed by their gestational age and Apgar score in the 1st and the 5th minute of life. They were all examined neurologically and by ultrasonography in the first week of life and, repeatedly, at the age of 1, 3, 6, 9, 12, 18, as well as in the 24th month of life. They were treated by the standard methods for this disease. Finally, all the infants were examined neurologically and by magnetic resonance imaging of the brain in their 3rd year of age. On the basis of neurological finding infants were devided into 3 groups: infants with normal neurological finding, infants with mild neurological symptomatology, and infants with severe neurological disorders. Results. It was shown that neurological finding, ultrasonography and magnetic resonance imaging of the brain positively correlated with the later neurological development of the infants with hypoxic-ischemic encephalopathy. Conclusion. Only the combined use of these techniques had full diagnostic and prognostic significance emphasizing that the integrative approach was very important in the diagnosis of brain lesions in infants. |
| format | Article |
| id | doaj-art-d98deef9f83c4a1b926eb1c84e838d21 |
| institution | OA Journals |
| issn | 0042-8450 |
| language | English |
| publishDate | 2003-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-d98deef9f83c4a1b926eb1c84e838d212025-08-20T02:03:47ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502003-01-0160329129710.2298/VSP0303291CHypoxic-ischemic encefalopathy: Clinical course and prognosisĆosić-Cerovac NatašaTodorović Slobodanka M.Jović Nebojša J.Prostran Milica Š.Background. Establishing the value of neurological examination, and additional diagnostic methods (ultrasonography and magnetic resonance imaging of the brain) in the diagnosis and prognosis of hypoxic-ischemic encephalopathy and its treatment, tracking the clinical course, and making the prognosis of neurological development in newborn infants with hypoxic-ischemic encefalopathy. Methods. The group of 40 term newborn infants with suspected intrauterine asphyxia was examined. All the infants were prospectivelly followed untill the 3rd year of age at the Clinic for Neurology and Psychiatry for Children and Youth in order to estimate their neurological development and to diagnose the occurence of persistent neurological disorders. All the infants were analyzed by their gestational age and Apgar score in the 1st and the 5th minute of life. They were all examined neurologically and by ultrasonography in the first week of life and, repeatedly, at the age of 1, 3, 6, 9, 12, 18, as well as in the 24th month of life. They were treated by the standard methods for this disease. Finally, all the infants were examined neurologically and by magnetic resonance imaging of the brain in their 3rd year of age. On the basis of neurological finding infants were devided into 3 groups: infants with normal neurological finding, infants with mild neurological symptomatology, and infants with severe neurological disorders. Results. It was shown that neurological finding, ultrasonography and magnetic resonance imaging of the brain positively correlated with the later neurological development of the infants with hypoxic-ischemic encephalopathy. Conclusion. Only the combined use of these techniques had full diagnostic and prognostic significance emphasizing that the integrative approach was very important in the diagnosis of brain lesions in infants.http://www.doiserbia.nb.rs/img/doi/0042-8450/2003/0042-84500303291C.pdfhypoxia-ischemiabrainneurologic examinationultrasonographymagnetic resonance imagingprognosis |
| spellingShingle | Ćosić-Cerovac Nataša Todorović Slobodanka M. Jović Nebojša J. Prostran Milica Š. Hypoxic-ischemic encefalopathy: Clinical course and prognosis Vojnosanitetski Pregled hypoxia-ischemia brain neurologic examination ultrasonography magnetic resonance imaging prognosis |
| title | Hypoxic-ischemic encefalopathy: Clinical course and prognosis |
| title_full | Hypoxic-ischemic encefalopathy: Clinical course and prognosis |
| title_fullStr | Hypoxic-ischemic encefalopathy: Clinical course and prognosis |
| title_full_unstemmed | Hypoxic-ischemic encefalopathy: Clinical course and prognosis |
| title_short | Hypoxic-ischemic encefalopathy: Clinical course and prognosis |
| title_sort | hypoxic ischemic encefalopathy clinical course and prognosis |
| topic | hypoxia-ischemia brain neurologic examination ultrasonography magnetic resonance imaging prognosis |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2003/0042-84500303291C.pdf |
| work_keys_str_mv | AT cosiccerovacnatasa hypoxicischemicencefalopathyclinicalcourseandprognosis AT todorovicslobodankam hypoxicischemicencefalopathyclinicalcourseandprognosis AT jovicnebojsaj hypoxicischemicencefalopathyclinicalcourseandprognosis AT prostranmilicas hypoxicischemicencefalopathyclinicalcourseandprognosis |