Bacteroides Fragilis Exacerbates T2D Vascular Calcification by Secreting Extracellular Vesicles to Induce M2 Macrophages

Bacteroides Fragilis Exacerbates T2D Vascular Calcification by Secreting Extracellular Vesicles to Induce M2 Macrophages

Abstract Vascular calcification (VC) in type 2 diabetes (T2D) poses a serious threat to the life and health of patients. However, its pathogenesis remains unclear, resulting in a lack of effective treatment for the root cause. It is found that both intestinal Bacteroides fragilis (BF) and peripheral...

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Bibliographic Details
Main Authors: Cong Chen, Zhengfeng Liang, Yuqi He, Yan Gao, Shuhui Ouyang, Lili Wang, Jianghua Liu, Jingsong Cao
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Advanced Science
Subjects:
Bacteroides fragilis
extracellular vesicles
macrophages
type 2 diabetes
vascular calcification
Online Access:https://doi.org/10.1002/advs.202410495
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