Niosome Preparation Techniques and Structure—An Illustrated Review

A comprehensive review of recent research on niosomes was conducted using a mixed methodology, including searches in databases such as Scopus, PubMed, and Web of Science (WoS). Articles were selected based on relevance. The current review examines the historical development of niosomes focusing on t...

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Main Authors: Saeid Mezail Mawazi, Yi Ge, Riyanto Teguh Widodo
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/17/1/67
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author Saeid Mezail Mawazi
Yi Ge
Riyanto Teguh Widodo
author_facet Saeid Mezail Mawazi
Yi Ge
Riyanto Teguh Widodo
author_sort Saeid Mezail Mawazi
collection DOAJ
description A comprehensive review of recent research on niosomes was conducted using a mixed methodology, including searches in databases such as Scopus, PubMed, and Web of Science (WoS). Articles were selected based on relevance. The current review examines the historical development of niosomes focusing on the methods of preparations and the contemporary strategies and prospective advancements within the realm of drug delivery systems, highlighting innovative approaches across transdermal, oral, and cellular delivery. This review reported the method of niosomes preparations including a new and novel approach for the preparation of niosomes known as the ball milling method (BM). This technique allows for the precise manipulation of size and shape, leading to improvements in drug release, encapsulation efficiency, and uniformity compared to traditional methods. Niosomes can serve as carriers for delivering various types of drugs, including hydrophobic, hydrophilic, and amphiphilic. This improves the efficiency of encapsulating different drugs, the size of targeted particles, and the desired zeta potential. This is achieved by using a specific charge-inducing agent for drug delivery and targeting specific diseases. These efforts are crucial for overcoming the current limitations and unlocking the full therapeutic potential of modern medicine.
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spelling doaj-art-d94f0468511d43229ce93323e7c0f5622025-01-24T13:45:48ZengMDPI AGPharmaceutics1999-49232025-01-011716710.3390/pharmaceutics17010067Niosome Preparation Techniques and Structure—An Illustrated ReviewSaeid Mezail Mawazi0Yi Ge1Riyanto Teguh Widodo2Department of Pharmaceutical Technology, Faculty of Pharmacy, Universiti Malaya, Kuala Lumpur 50603, MalaysiaSchool of Pharmacy, Queen’s University Belfast, Belfast BT9 7BL, UKDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Universiti Malaya, Kuala Lumpur 50603, MalaysiaA comprehensive review of recent research on niosomes was conducted using a mixed methodology, including searches in databases such as Scopus, PubMed, and Web of Science (WoS). Articles were selected based on relevance. The current review examines the historical development of niosomes focusing on the methods of preparations and the contemporary strategies and prospective advancements within the realm of drug delivery systems, highlighting innovative approaches across transdermal, oral, and cellular delivery. This review reported the method of niosomes preparations including a new and novel approach for the preparation of niosomes known as the ball milling method (BM). This technique allows for the precise manipulation of size and shape, leading to improvements in drug release, encapsulation efficiency, and uniformity compared to traditional methods. Niosomes can serve as carriers for delivering various types of drugs, including hydrophobic, hydrophilic, and amphiphilic. This improves the efficiency of encapsulating different drugs, the size of targeted particles, and the desired zeta potential. This is achieved by using a specific charge-inducing agent for drug delivery and targeting specific diseases. These efforts are crucial for overcoming the current limitations and unlocking the full therapeutic potential of modern medicine.https://www.mdpi.com/1999-4923/17/1/67preparationniosomesmethodsreviewsurfactantstechnique
spellingShingle Saeid Mezail Mawazi
Yi Ge
Riyanto Teguh Widodo
Niosome Preparation Techniques and Structure—An Illustrated Review
Pharmaceutics
preparation
niosomes
methods
review
surfactants
technique
title Niosome Preparation Techniques and Structure—An Illustrated Review
title_full Niosome Preparation Techniques and Structure—An Illustrated Review
title_fullStr Niosome Preparation Techniques and Structure—An Illustrated Review
title_full_unstemmed Niosome Preparation Techniques and Structure—An Illustrated Review
title_short Niosome Preparation Techniques and Structure—An Illustrated Review
title_sort niosome preparation techniques and structure an illustrated review
topic preparation
niosomes
methods
review
surfactants
technique
url https://www.mdpi.com/1999-4923/17/1/67
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